DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14997 and Sqor

DIOPT Version :9

Sequence 1:	NP_647877.1	Gene:	CG14997 / 38514	FlyBaseID:	FBgn0035515	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001041378.2	Gene:	Sqor / 691966	RGDID:	1564504	Length:	450	Species:	Rattus norvegicus

Alignment Length:	438	Identity:	218/438 - (49%)
Similarity:	295/438 - (67%)	Gaps:	16/438 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLLATHNHAPTAFSTRFLSTSRVNRERQECQVLVVGGGTGGCAMAAKLSSRLGSDKVVVLEPEDK 79
            |.|.|....|....|....|::.:.|     |||:|||:||..||.::..|:|::.|.::||.::
  Rat    20 LRLGTQQAGPLQLHTGACCTAKNHYE-----VLVLGGGSGGITMATRMKRRVGAENVAIVEPSER 79

  Fly    80 HYYQPMFTLIGGGMKRLDQSHRQMADVLPTKAKWVKEKALEFDPDNNTVSTSGGKTIKYDFLIIA 144
            |:|||::||:|.|.|.|..|.|....|:|:..:|::::..|.:||.|.:.|..||.|.|.:||||
  Rat    80 HFYQPIWTLVGAGAKELSSSDRSTLSVIPSGVQWIQDRVAELNPDQNCIRTDNGKEISYRYLIIA 144

  Fly   145 TGLQLNYGKIPGLVEALETPDSNVCSIYSPKYVDHVYECLRRTNKGNAIFTFPNCPIKCAGAPQK 209
            .|:||:|.||.||.|....|  .:.|.||.|.|:..::.|:...:|||:|||||.|:||||||||
  Rat   145 LGIQLDYEKIKGLPEGFAYP--KIGSNYSVKTVEKTWKALQDFKEGNALFTFPNTPVKCAGAPQK 207

  Fly   210 IAYISEHYFRKMGRRDNVNIIYNTSLPVIFGVKHYAEALMKLIKRRNITLNVQRNLVEVRHKDNI 274
            |.|:||.||||.|:|...|||:||:|..|||||.||:||.::|:.||:::|.:.||:|||.....
  Rat   208 IMYLSEAYFRKTGKRSKANIIFNTALGTIFGVKKYADALQEIIRERNVSVNYKHNLIEVRADKQE 272

  Fly   275 AVFEDLAKPG----VHYEETYSMLHVTPPMSTPDVVANCKKLVTPTGFVDVDQLTLQHNKYSNVF 335
            ||||:|.|||    :|||    |||||||||:|||:.. ..:....|:||||:.||||.||.|||
  Rat   273 AVFENLDKPGETHVIHYE----MLHVTPPMSSPDVLKR-SPVADSAGWVDVDKETLQHKKYPNVF 332

  Fly   336 AIGDSASSPNSKTAAAAAAQSPVVFKNVMAAIEGKAPTDIYDGYSSCPIVTGYSSCILAEFDYNL 400
            .|||..:.|.||||||.||||.::.:.:...::.:.||..||||:|||:||||:..|||||||..
  Rat   333 GIGDCTNLPTSKTAAAVAAQSGILDRTISLIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYTA 397

  Fly   401 TPVETFPLDQSKERYSMFFMKKELMPVLYWKLMMNGYWNGPALMRKIF 448
            .|:||||.||||||.||:.||.::||.|||.:|:.|||.|||.:||:|
  Rat   398 QPLETFPFDQSKERISMYLMKADMMPFLYWNMMLRGYWGGPAFLRKLF 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14997	NP_647877.1	Pyr_redox_2	59..342	CDD:285266	141/286 (49%)
Sqor	NP_001041378.2	FadH2	46..425	CDD:223523	198/385 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352932
Domainoid	1	1.000	206	1.000	Domainoid score	I2813
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10921
Inparanoid	1	1.050	444	1.000	Inparanoid score	I1588
OMA	1	1.010	-	-		QHG62271
OrthoDB	1	1.010	-	-		D1267127at2759
OrthoFinder	1	1.000	-	-		FOG0005877
OrthoInspector	1	1.000	-	-		oto96582
orthoMCL	1	0.900	-	-		OOG6_102907
Panther	1	1.100	-	-	LDO	PTHR10632
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4272
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810