Protein Alignment Ero1L and ero1a

DIOPT Version :10

• Sequence 1: NP_647865.2
• Gene: Ero1L / 38500
• FlyBaseID: FBgn0261274
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001016058.1
• Gene: ero1a / 548812
• XenbaseID: XB-GENE-978124
• Length: 474
• Species: Xenopus tropicalis
• Alignment Length: 489
• Identity: 226/489 - (46%)
• Similarity: 309/489 - (63%)
• Gaps: 52/489 - (10%)

  Fly    14 AAVVLVLLLLWTDTTGGYFAAIDETETSKNCFCELEGSINDCSCDVDTVDHFNNMKIYPRLQSLL 78
            :.:||..||||     |..:..:::..::.|||::.|.::||:|||:|:|||||..::|:||.|:
 Frog    15 SVLVLCSLLLW-----GSNSQQEQSSAAQRCFCQVTGYLDDCTCDVETIDHFNNYGLFPKLQQLV 74

  Fly    79 VKNFFRFYKVNLRQECPFWPDDSRCAMRFCQVENCEEQAIPQGIKDKGEHKEKAAFKYTREAQVG 143
            ..::||:||.||::.||||.|:|.|.::.|.|:.|....:| |:|..|       ||||.||...
 Frog    75 ASDYFRYYKANLKKPCPFWEDNSHCGVKDCAVKPCPTDEVP-GLKPPG-------FKYTEEANRA 131

  Fly   144 GSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDDHEE-GSQYVDLLLNPERY 207
            .....|.|. :..|..:|.|:|.:|......|.:||::.::||.:||.|. .::|||||.|||||
 Frog   132 HEEIDDCEK-EKRLSAVDESLSVEAQEAMLKWNRHDDSADNFCELDDEESPDAEYVDLLKNPERY 195

  Fly   208 TGYKGESAHRIWKSIYLENCF---------------GGNNETANKFSNYVPHLDLRNVCLEQRAF 257
            |||||....|||.|||.||||               .|.|| ...|.|:     |..:|:|:|||
 Frog   196 TGYKGADTWRIWNSIYEENCFKPKAVQRPLNPLTSTRGENE-GKVFYNW-----LDGLCVEKRAF 254

  Fly   258 YRIISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIY 322
            ||:|||||:|||||||:.|||.::  ::|.  |||.|..||::||....|.||||..|:||||||
 Frog   255 YRLISGLHASINIHLCANYLLKDT--WMDK--IWGHNTAEFQKRFDATLTQGEGPKRLKNLYFIY 315

  Fly   323 LIELRALAKAAPYLRREDY--YTGIAEEDDEVKLAINDMLSVIENFQSHFDENALFS-NGIASIK 384
            ||||||::|..|:..|..:  |||...:|.|.|..:.|:|....:|..|||||:||| :...:.|
 Frog   316 LIELRAISKVLPFFERSSFLLYTGNETKDTETKKLLLDVLLDARDFPLHFDENSLFSGDKKEAAK 380

  Fly   385 FKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEK-LNLATESGLWDKPHIEAD 448
            .|.|:::.|||||:||.||||.||:|||||||||||||||||:||: :...:||   ::|
 Frog   381 LKEDFRQHFRNISKIMDCVGCFKCRLWGKLQTQGLGTALKILFSERQIENLSES---NQP----- 437

  Fly   449 PIFRLSRTEIVALFNAFGRLSNSIYEMENFRCVL 482
            ..|.|:|.|||||||||.|:|.|:.|:||||.:|
 Frog   438 SEFHLTRQEIVALFNAFARISTSVKELENFRTLL 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ero1L	NP_647865.2	ERO1	69..475	CDD:461191	198/425 (47%)
ero1a	NP_001016058.1	ERO1	66..464	CDD:461191	198/424 (47%)