Protein Alignment Ero1L and ero-1

DIOPT Version :10

• Sequence 1: NP_647865.2
• Gene: Ero1L / 38500
• FlyBaseID: FBgn0261274
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001364667.1
• Gene: ero-1 / 173325
• WormBaseID: WBGene00001334
• Length: 513
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 197/507 - (38%)
• Similarity: 283/507 - (55%)
• Gaps: 71/507 - (14%)

  Fly    16 VVLVLLLLWTDTTGGYFAAIDETETSKNCFCELEGSINDCSCD-VDTVDHFNNMKIYPRLQSLLV 79
            :||.|:::..:|         :.|:.:.|||:...::..|.|. ..|:|..||.:||.::|.||.
 Worm     9 IVLSLIIIVVNT---------QFESGRLCFCKGFEAVEPCDCSKPQTIDKLNNHRIYEKVQKLLK 64

  Fly    80 KNFFRFYKVNLRQECPFWPDDSRCAMRFCQVENCEEQAIPQGIKDKG------------------ 126
            |:||||||||:.:.||||.||.:|....|.:..|::: :|.|::.:.
 Worm    65 KDFFRFYKVNMDKTCPFWADDRQCGTNQCGIAFCDDE-VPAGLRRRNAVNMVRRSSHESSHEISE 128

  Fly   127 EHKEKAAFKYTREAQVG-----GSACSDGEDFD--------SSLGFLDTSISDQAHREFELWAKH 178
            .|......::....::|     .:|..:.||.|        :::..:|.::.|...|:.:....|
 Worm   129 NHNNNRQQRWNETTKIGVIVQEAAAVKEEEDDDAEKCADAGNNIDPMDRTLHDDEKRQLDAMDHH 193

  Fly   179 DEAEED-FC-IVDDHEEGSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCFGGNNETANKF-SN 240
            |:..|| || |.||..:|..||||..||||||||.|:|..|:|||||.||||    :...|| .|
 Worm   194 DDGLEDKFCEIEDDESDGMHYVDLSKNPERYTGYAGKSPQRVWKSIYEENCF----KPDPKFDKN 254

  Fly   241 YVPHLDLRNVCLEQRAFYRIISGLHSSINIHLCS---KYLLSESKDFLDPQGIWGPNVKEFKRRF 302
            ::.:.....:|||:|.|||:||||||:|.|.:.:   |........|....|.|..|.:.|..||
 Worm   255 FLTNPSNFGMCLEKRVFYRLISGLHSAITISIAAYNYKPPPPSLGQFGSQMGTWFRNTEMFAGRF 319

  Fly   303 SPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRREDYYTGIAEEDDEVKLAINDMLSVIENFQ 367
            ..: .|.|||..|||:|||||:|||||.||||||:.|.:|||...||.|.:.|:.|:|..|..:.
 Worm   320 GTK-WSWEGPQRLRNVYFIYLLELRALLKAAPYLQNELFYTGNDVEDAETRKAVEDLLEEIRAYP 383

  Fly   368 SHFDENALFSNGIAS--IKFKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEK 430
            :||||:.:|: |:.|  ...:.:::..|.||||||.||.||||:||||:||.|:|||||||:|
 Worm   384 NHFDESEMFT-GVESHARALREEFRSHFVNISRIMDCVECDKCRLWGKVQTHGMGTALKILFS-- 445

  Fly   431 LNLATESGLWDKPHI---EADPIFRLSRTEIVALFNAFGRLSNSIYEMENFR 479
                      |.||.   :....|:|:|.|:|||..:|||.|:||.|::|||
 Worm   446 ----------DLPHSHYKQDSSKFQLTRNEVVALLQSFGRYSSSILEVDNFR 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ero1L	NP_647865.2	ERO1	69..475	CDD:461191	179/447 (40%)
ero-1	NP_001364667.1	ERO1	54..483	CDD:461191	179/447 (40%)