Protein Alignment Ras64B and DIRAS3

DIOPT Version :10

• Sequence 1: NP_523917.2
• Gene: Ras64B / 38494
• FlyBaseID: FBgn0003206
• Length: 192
• Species: Drosophila melanogaster
• Sequence 2: NP_004666.1
• Gene: DIRAS3 / 9077
• HGNCID: 687
• Length: 229
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 56/197 - (28%)
• Similarity: 101/197 - (51%)
• Gaps: 7/197 - (3%)

  Fly     2 QMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEF 66
            :::.|::||||..|||||.:..::....|..:|.||||::|.:..........|.|.|:...:..
Human    34 KIRDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGN 98

  Fly    67 SAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRD--EFPMLMVGNKCDLKHQQQVS 129
            .|::...:..|..|:||:::....:.:|:..|...|.::|..:  :||:::||||.|..| ::|:
Human    99 RALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSDDTH-REVA 162

  Fly   130 LEEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRK----FQIAERPFIEQDYKKKGKRKCC 190
            |.:....:......::|.|||..|||.:.||.|:...:|    .|..|:.....:..:|...||.
Human   163 LNDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKKSQMPNTTEKLLDKCI 227

  Fly   191 LM 192
            :|
Human   228 IM 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ras64B	NP_523917.2	M_R_Ras_like	4..167	CDD:133345	49/164 (30%)
DIRAS3	NP_004666.1	P-loop containing Nucleoside Triphosphate Hydrolases	37..200	CDD:476819	49/163 (30%)
		Effector region. /evidence=ECO:0000255	66..74		5/7 (71%)