Protein Alignment CG11594 and glpK

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_418361.1
• Gene: glpK / 948423
• ECOCYCID: EG10398
• Length: 502
• Species: Escherichia coli
• Alignment Length: 568
• Identity: 122/568 - (21%)
• Similarity: 205/568 - (36%)
• Gaps: 126/568 - (22%)

  Fly     1 MSSGPFFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVI 65
            |:...:.|.:|.||.|:||.::..|..::..:.:..:...|:||:.......||.:....:.:|:
E. coli     1 MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVL 65

  Fly    66 GGVDKSKVKGIGFDATCSLVVLGPQGSPLTVSK-SGEAEQNIILWMDHRAEQETQEINAFKHSLL 129
            ...|      |..|...::.:...:.:.:...| :|:...|.|:|...|..:..:.:.  :..|.
E. coli    66 AKAD------ISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLK--RDGLE 122

  Fly   130 KYVGGQVSLEMEV----PKLLWL----------KRNLSQTFGNI--WRVFDLPDFLTWRAT---- 174
            .|:.....|.::.    .|:.|:          .|.....||.:  |        |.|:.|
E. coli   123 DYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTW--------LIWKMTQGRV 179

  Fly   175 GVDTRSLCSVVCKWNYDAANGSWNKEFLKQADL--EELTQNNFEKLGSDVQPPGRTVGKGLTAKA 237
            .|...:..|....:|....:  |:.:.|:..|:  |.|.:   .:..|:|.......|||
E. coli   180 HVTDYTNASRTMLFNIHTLD--WDDKMLEVLDIPREMLPE---VRRSSEVYGQTNIGGKG----- 234

  Fly   238 AGELGLSAGTVVSTSLI--DAHAGALGMF-------------GCRSKESKGADDVQGKMALIAGT 287
                    ||.:..|.|  |..|...|..             ||....:.|...|:.:..|
E. coli   235 --------GTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGL---- 287

  Fly   288 STCHMSITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAG----HLLDHVLKSHESYAELKSQLG 348
                  :|..||      ||..:.   .|.| ||...:||    .|.|.:...:::|       .
E. coli   288 ------LTTIAC------GPTGEV---NYAL-EGAVFMAGASIQWLRDEMKLINDAY-------D 329

  Fly   349 EDKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTES 413
            .:.|..:..|                  |..|:|.|...|..:|..||..||.|.||  |||..:
E. coli   330 SEYFATKVQN------------------TNGVYVVPAFTGLGAPYWDPYARGAIFGL--TRGVNA 374

  Fly   414 LAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQE 478
            ..| ..|.::::||.||.::|.:..........|...||...|...:|..:||.......|:.:|
E. coli   375 NHI-IRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVRE 438

  Fly   479 MVLVGAAALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEFHNRKY 526
            :..:|||.|...|.|.:.:|:...:. ....:..:|..||.| .|.:|
E. coli   439 VTALGAAYLAGLAVGFWQNLDELQEK-AVIEREFRPGIETTE-RNYRY 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	121/563 (21%)
glpK	NP_418361.1	glpK	1..498	CDD:234594	122/568 (21%)