Protein Alignment CG11594 and lsrK

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_416028.3
• Gene: lsrK / 946069
• ECOCYCID: G6798
• Length: 530
• Species: Escherichia coli
• Alignment Length: 588
• Identity: 130/588 - (22%)
• Similarity: 208/588 - (35%)
• Gaps: 173/588 - (29%)

  Fly     6 FFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWN----PE-PGYYNQSSDNIWQSICQVVKKVI 65
            :.:.:|.||||.||.:...:|..:  ||...: |.    |: ||......:..||..|:.:::.:
E. coli    13 YLMALDAGTGSIRAVIFDLEGNQI--AVGQAE-WRHLAVPDVPGSMEFDLNKNWQLACECMRQAL 74

  Fly    66 --GGVDKSKVKGIGFDATCS----LVVLGPQGSPLTVSKSGEAEQNIILW----MDHRAEQETQE 120
              .|:....:..:   :.||    :|:...:|:|              :|    :|.||.:|..|
E. coli    75 HNAGIAPEYIAAV---SACSMREGIVLYNNEGAP--------------IWACANVDARAAREVSE 122

  Fly   121 I-----NAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFGNIWRVFDLPDFLTWRATG---VD 177
            :     |.|::.:.:..|..::|. .:|:||||..:.|..:.....:..:.|:|.:..:|   ||
E. coli   123 LKELHNNTFENEVYRATGQTLALS-AIPRLLWLAHHRSDIYRQASTITMISDWLAYMLSGELAVD 186

  Fly   178 -----TRSLCSVVCKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGK--GLTA 235
                 |..|        .|.....|....|..|.|.           :|:..|.:..|.  |:.:
E. coli   187 PSNAGTTGL--------LDLTTRDWKPALLDMAGLR-----------ADILSPVKETGTLLGVVS 232

  Fly   236 KAAGEL-GLSAGTVVSTSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTSTCHMSITRKAC 299
            ..|.|| ||.|||.|..                     |..|||                  ..|
E. coli   233 SQAAELCGLKAGTPVVV---------------------GGGDVQ------------------LGC 258

  Fly   300 FAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLD---------HVLKSHESYAELKSQLG------- 348
            ...||..|.|.|::.|.|..: ..::|..:.|         ||:........:....|
E. coli   259 LGLGVVRPAQTAVLGGTFWQQ-VVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFR 322

  Fly   349 -----EDKFIYQHLN----KLLPELAA-----ARGLSQVGCLTQDVHVWPDLHGNRSPI---ADP 396
                 |:|.|.:.|.    .||.|:|:     :.|:..:.........|  .|...|.|   .||
E. coli   323 DAFCAEEKLIAERLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTW--YHAAPSFINLSIDP 385

  Fly   397 TLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQ 461
            ......|   :.|..|..|    |.|.|..      ::.:..:......:|:|.||.:|..|:.|
E. coli   386 DKCNKAT---LFRALEENA----AIVSACN------LQQIADFSNIHPSSLVFAGGGSKGKLWSQ 437

  Fly   462 CHADICNLPALIPDEQEMVLVGAAALGAAASGHFDSLESASKSMGGTGQ-LVK------PNAETL 519
            ..||:..||..||..:|...:|.|......:|.|       .||..||: ||:      |:.|..
E. coli   438 ILADVSGLPVNIPVVKEATALGCAIAAGVGAGIF-------SSMAETGERLVRWERTHTPDPEKH 495

  Fly   520 EFH 522
            |.:
E. coli   496 ELY 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	130/588 (22%)
lsrK	NP_416028.3	PRK10939	10..530	CDD:182853	130/588 (22%)