Protein Alignment CG11594 and YDR109C

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_010394.3
• Gene: YDR109C / 851687
• SGDID: S000002516
• Length: 715
• Species: Saccharomyces cerevisiae
• Alignment Length: 682
• Identity: 236/682 - (34%)
• Similarity: 339/682 - (49%)
• Gaps: 158/682 - (23%)

  Fly     6 FFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVI--GGV 68
            |:||||||||||||.::...|.:|..|.:.|:.......:..|||..||.::|..|:.|:  .||
Yeast    39 FYVGVDVGTGSARACVIDQSGNMLSLAEKPIKREQLISNFITQSSREIWNAVCYCVRTVVEESGV 103

  Fly    69 DKSKVKGIGFDATCSLVV----------LGPQGSPLTVSKSGEAEQNIILWMDHRAEQETQEINA 123
            |..:|:||||||||||||          :||..:        ..:|||||||||||.:||:|||:
Yeast   104 DPERVRGIGFDATCSLVVVSATNFEEIAVGPDFT--------NNDQNIILWMDHRAMKETEEINS 160

  Fly   124 FKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFGNIWRVFDLPDFLTWRATGVDTRSLCSVVCKW 188
            .....|||||||:|:|||:||:.|||.||........:.|||||:||::|||.:.||.||.|||.
Yeast   161 SGDKCLKYVGGQMSVEMEIPKIKWLKNNLEAGIFQDCKFFDLPDYLTFKATGKENRSFCSAVCKQ 225

  Fly   189 NY-----DAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKG-----LTAKAAGELGL 243
            .:     :.::..|:||||....|.|||:|:||:||..::.....:..|     |..|||.:|||
Yeast   226 GFLPVGVEGSDIGWSKEFLNSIGLSELTKNDFERLGGSLREKKNFLTAGECISPLDKKAACQLGL 290

  Fly   244 SAGTVVSTSLIDAHAGALGMFGCRSKES-KGADDVQ----------GKMALIAGTSTCHMSITRK 297
            :...|||:.:|||:||.:|....:.:.: ||..:.:          |::|.:|||||||:.:::.
Yeast   291 TEHCVVSSGIIDAYAGWVGTVAAKPESAVKGLAETENYKKDFNGAIGRLAAVAGTSTCHILLSKN 355

  Fly   298 ACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELK---SQLGEDKFIYQHLNK 359
            ..|..||||||:|.:..|::..|||||..|.||||::.:|.::.||.   :..|..||  ::|||
Yeast   356 PIFVHGVWGPYRDVLARGFWAAEGGQSCTGVLLDHLITTHPAFTELSHMANLAGVSKF--EYLNK 418

  Fly   360 LLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQA 424
            :|..|...|.:..|..|.:.:..:.|.||||||||||.:|..|.|..|....|.||:.||:..:.
Yeast   419 ILETLVEKRKVRSVISLAKHLFFYGDYHGNRSPIADPNMRACIIGQSMDNSIEDLAVMYLSACEF 483

  Fly   425 LAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLV-GAAALG 488
            ::..||.|||.:.:.|. ....:...||..:|.|.::..||...||.:||...:..:| |:|.||
Yeast   484 ISQQTRQIIEVMLKSGH-EINAIFMSGGQCRNSLLMRLLADCTGLPIVIPRYVDAAVVFGSALLG 547

  Fly   489 AAASGHFD--------------------------------------------------------- 496
            ||||..||
Yeast   548 AAASEDFDYTREKRTLKGQKSSQTKTERFNDSYSSIQKLSMEDRNSTNGFVSPHNLQLSTPSAPA 612

  Fly   497 --------------------------SLESASKSMG------------------GTGQLVKPNAE 517
                                      ||....:|:|                  |..::|.||.:
Yeast   613 KINNYSLPICTQQPLDKTSEESSKDASLTVGQESLGEGRYNGTSFLWKVMQELTGNARIVNPNEK 677

  Fly   518 TLEFH------NRKYKVFLQLLENQRQYRRIM 543
            |   |      :.||::||.::|.||:|||::
Yeast   678 T---HPDRILLDTKYQIFLDMIETQRKYRRMV 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	233/677 (34%)
YDR109C	NP_010394.3	ASKHA_NBD_FGGY_D-RBK	39..703	CDD:466800	233/677 (34%)