Protein Alignment CG11594 and Gk

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_008771496.1
• Gene: Gk / 79223
• RGDID: 70893
• Length: 587
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 140/613 - (22%)
• Similarity: 223/613 - (36%)
• Gaps: 173/613 - (28%)

  Fly     4 GPFFVGVDVGTGSARAALV-ACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKV--- 64
            ||....||.||.|.|..:. :....:|......|:...|..|:..|....|.||:.:.::|.
  Rat    10 GPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILQSVYECIEKTCEK 74

  Fly    65 IG--GVDKSKVKGIG-------------------FDATCSLVVLG--------PQGSPLTVSKSG 100
            :|  .:|.|.:|.||                   ::|..:.|..|        |.|||:..:.:.
  Rat    75 LGQLNIDISNIKAIGVSNQRETTVVWDKLTGEPLYNAVAAPVSPGSSVPVAVVPSGSPVPAAGAS 139

  Fly   101 EAEQNIILWMDHRAEQETQEI-------NAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQT--- 155
            .      :|:|.|.:...:::       |.|..|   ..|..:|......||.||..|:.:.
  Rat   140 S------VWLDLRTQSTVEKLSKRIPGNNNFVKS---KTGLPLSTYFSAVKLRWLLDNVKKVQEA 195

  Fly   156 -------FGNIWRVFDLPDFLTWRAT-GVDTRSLCSVVCKWNYDAANGS-----------WNKEF 201
                   ||.|      ..:|.|..| |::....|:       |..|.|           |:||.
  Rat   196 VEENRALFGTI------DSWLIWSLTGGINGGVHCT-------DVTNASRTMLFNIHSLEWDKEL 247

  Fly   202 LKQADLEELTQNNFEKLGSDVQPPGRTVGK--GL-----TAKAAGELGLSAGTVVSTSLIDAHAG 259
            .:           |..:..::.|..|:..:  ||     :.||    |...|..:|..|.|..|.
  Rat   248 CE-----------FFGIPMEILPNVRSSSEIYGLMKISHSLKA----GALEGVPISGCLGDQSAA 297

  Fly   260 ALGMFGCRSKESKGADDVQGKMALIAGTSTCHMSITRKACFAQGVWGPY-----------QDAII 313
            .:|....:..::|..          .||....:..|...|    |:..:           :|.
  Rat   298 LVGQMCFQDGQAKNT----------YGTGCFLLCNTGHKC----VFSEHGLLTTVAYKLGRDK-- 346

  Fly   314 PGYFLNEGGQSIAGHLL----DH--VLKSHESYAELKSQLGEDKFIYQHLNKLLPELAAARGLSQ 372
            |.|:..||..:|||.::    |:  ::||.|...:|..::|                      :.
  Rat   347 PVYYALEGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVG----------------------TS 389

  Fly   373 VGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLY 437
            .||     :..|...|..:|..:|:.||:|.||  |:.|....|.:.| ::|:.:.||.|::.:.
  Rat   390 YGC-----YFVPAFSGLYAPYWEPSARGIICGL--TQFTNKCHIAFAA-LEAVCFQTREILDAMN 446

  Fly   438 QYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGAA-ALGAAASGHFDSLESA 501
            :....|...|...||:..|.:.:|..|||..:|.:.|...|...:||| |.|||......|||..
  Rat   447 RDCGIPLSHLQVDGGMTSNKILMQLQADILYIPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPE 511

  Fly   502 SKSMGGTGQLVKP--NAETLEFHNRKYK 527
            ..| ..|.:..:|  |||..|.....:|
  Rat   512 DLS-AVTMERFEPQINAEESEIRYSTWK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	138/611 (23%)
Gk	XP_008771496.1	ASKHA_NBD_FGGY_GK1-3-like	11..544	CDD:466802	139/612 (23%)