Protein Alignment CG11594 and PSMC5

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_002796.4
• Gene: PSMC5 / 5705
• HGNCID: 9552
• Length: 406
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 45/218 - (20%)
• Similarity: 72/218 - (33%)
• Gaps: 79/218 - (36%)

  Fly    27 RVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVIGGVDKSKVKGIGFDATCSLVVLGPQG 91
            |:|.:.:|.:|    |.|.|              |.:|:..:||.||          ||.:.|:|
Human    57 RLLREELQLLQ----EQGSY--------------VGEVVRAMDKKKV----------LVKVHPEG 93

  Fly    92 SPLTVSKSGEAEQNIILWMDHRAEQETQEINAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTF 156
            ..:.     :.::||             :||....:.      :|:|..:...|..:..|.....
Human    94 KFVV-----DVDKNI-------------DINDVTPNC------RVALRNDSYTLHKILPNKVDPL 134

  Fly   157 GNIWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSD 221
            .::..|..:||.......|:|.:.                  ||..:..:|.......||.||..
Human   135 VSLMMVEKVPDSTYEMIGGLDKQI------------------KEIKEVIELPVKHPELFEALGIA 181

  Fly   222 -------VQPPGRTVGKGLTAKA 237
                   ..|||  .||.|.|:|
Human   182 QPKGVLLYGPPG--TGKTLLARA 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	45/218 (21%)
PSMC5	NP_002796.4	PRK03992	24..400	CDD:179699	45/218 (21%)
		May mediate interaction with PRPF9. /evidence=ECO:0000250|UniProtKB:P62196	186..406		8/19 (42%)