Protein Alignment CG11594 and Gk2

DIOPT Version :10

• Sequence 1: NP_647848.2
• Gene: CG11594 / 38473
• FlyBaseID: FBgn0035484
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_321549.2
• Gene: Gk2 / 1281605
• VectorBaseID: AGAMI1_001701
• Length: 555
• Species: Anopheles gambiae
• Alignment Length: 568
• Identity: 125/568 - (22%)
• Similarity: 200/568 - (35%)
• Gaps: 128/568 - (22%)

  Fly    10 VDVGTGSARAAL--------VACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSI-------CQ 59
            :|.||.|.|..:        :|.....:.|.|       |..|:...:...:.:::       |.
Mosquito    13 IDAGTNSVRFVIFKLPEFEEIASHQIRITQIV-------PRDGWTEHNPVEVLEAVRLCAVEACH 70

  Fly    60 VVKKVIGGVDKSKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWMDHRAEQETQEINA- 123
            .|:|:  |.....:..||........|:..:       .:||...|.|:|.|.|.::....:.|
Mosquito    71 QVEKL--GFLVKDIAAIGITNQRETTVVWDK-------NTGEPLYNAIVWNDIRTDKTVDRVLAR 126

  Fly   124 ---FKHSLLKYVGG-QVSLEMEVPKLLWLKRNLSQT----------FGNI--WRVFDLPDFLTWR 172
               ..|:..:.:.| .:|......||.|||.|:...          .|.|  |        |.|.
Mosquito   127 LPEQNHNHFRALSGLPISPYFSALKLNWLKDNVVAVRKACRERRCYAGTIDTW--------LVWN 183

  Fly   173 ATGVDTRSLCSVVCKWNYDAANGS----WNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKGL 233
            .||.....      .:..|..|.|    .|.|.|....|...|.:....:..:::......||
Mosquito   184 LTGGPQGG------AFVTDVTNASRTLLMNIETLHWDPLLTKTFSVHPDMLPEIRSSSEIYGK-- 240

  Fly   234 TAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTST-C----HMS 293
             .|.:..|.   |..:|..|.:..|..:|. .| .||.:..:..:....|:..|.| |    |..
Mosquito   241 -VKDSSVLD---GIPISAILGNQQASLVGQ-RC-LKEGQAKNTYRKGCFLLYNTGTRCVQSTHGL 299

  Fly   294 ITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGEDKFIYQHLN 358
            :|..| :..|...|      |.|.| ||..::||..::.:..:.:...::|..
Mosquito   300 VTTVA-YQMGRNAP------PIYAL-EGSVAVAGVAMNWLRDNLKIIKDIKDS------------ 344

  Fly   359 KLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKY---LA 420
               .|:|.:  :|..|    ||:..|...|..:|......||:..||      .|...|:   .|
Mosquito   345 ---EEIAGS--VSSTG----DVYFVPAFTGLYAPYWRKDARGIFCGL------TSFTTKHHFVRA 394

  Fly   421 FVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGAA 485
            .::|:.:.||.|||.:.:........|...|.:|.|.|.:|..||:..:|.|..:..|...:|.|
Mosquito   395 ALEAVCFQTRDIIEAMKKDCGINLNKLHTDGIMASNSLLMQLQADLSGIPVLRTEVHEPAALGTA 459

  Fly   486 ALGAAASG-HFDSLESASKSMGGTGQLVKPNAETL------EFHNRKY 526
            ...|.|:| ....||:..:...|    |:.:.||.      |..|.:|
Mosquito   460 MAAAQANGVDLYKLEAEIRGYAG----VQSHHETFLPTTTEEERNARY 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11594	NP_647848.2	5C_CHO_kinase	6..540	CDD:273552	125/568 (22%)
Gk2	XP_321549.2	None