Protein Alignment CG12766 and KCNAB3

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: XP_047293000.1
• Gene: KCNAB3 / 9196
• HGNCID: 6230
• Length: 460
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 79/342 - (23%)
• Similarity: 121/342 - (35%)
• Gaps: 81/342 - (23%)

  Fly     2 TGK---VEYYFKHNDGTHIQGIGLG---TFASTEGDCERAVLHAIDVGYRH----IDTAYFYG-- 54
            ||:   ::|......|..:..:|||   ||.|...|  ......:.|.|.|    .|||..|.
Human    72 TGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISD--ETAEDVLTVAYEHGVNLFDTAEVYAAG 134

  Fly    55 -NEAEVGAAVRKKIAEGVIKREDIFITTKL-WCNFHEPER------VEYACRKTLKNIGLDYVDL 111
             .|..:|..::.|    ..:|....||||: |....|.||      :....|.:|:.:.|.|||:
Human   135 KAERTLGNILKSK----GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195

  Fly   112 YLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRL 176
            ...:              ..|.|..:|       :...||..:::.||....|.|.:...::...
Human   196 VFAN--------------RSDPNCPME-------EIVRAMTYVINQGLALYWGTSRWGAAEIMEA 239

  Fly   177 LANCK----IKPIHNQIEVHPALDQK---KLIALCKKNGILVTAFSPLGRHNAELRTPTFMYDGK 234
            .:..:    |.|:..|.|.|....:|   :|..|..|.|:....:.||.     ....|..|||:
Human   240 YSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLA-----CGLITSKYDGR 299

  Fly   235 V-----------QAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFDFKLDAEDHA 288
            |           |.:.||......:.....|::|    ||.:.     :....|....:.||...
Human   300 VPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDL----LPVAH-----QLGCTVAQLAIGAEPAD 355

  Fly   289 ILDSYHNGERVAHARQA 305
            ..||  :|.|.|..:||
Human   356 PADS--DGNRRAPGKQA 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	73/326 (22%)
KCNAB3	XP_047293000.1	AKR_SF	76..349	CDD:444925	68/313 (22%)