Protein Alignment CG12766 and AKR1E2

DIOPT Version :9

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: XP_011518017.1
• Gene: AKR1E2 / 83592
• HGNCID: 23437
• Length: 341
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 137/308 - (44%)
• Similarity: 178/308 - (57%)
• Gaps: 22/308 - (7%)

  Fly    27 STEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKREDIFITTKLWCNFHEPE 91
            ::.|....||..|||.||||.|.||||.||.||||.:|.||.||.::|||:||.|||||..|:..
Human    35 ASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKS 99

  Fly    92 RVEYACRKTLKNIGLDYVDLYLIHWPFSYK------YRGDNEL-----------IPKDANGEVEL 139
            .||.||||:||.:.|:|:||||||||..:|      ....:||           :|.|.:..|..
Human   100 LVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIP 164

  Fly   140 VDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLIA 202
            .|.|:||||.|||.||..||.|:|||||||.|||.|||  ...:.||:.||||.||.|.||.||:
Human   165 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLIS 229

  Fly   203 LCKKNGILVTAFSPLGRHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSN 267
            .|:...:.|||:.|||   ........:.:..::.||.::.||.||::||:.|:...|.:|.|..
Human   230 FCQSRDVSVTAYRPLG---GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSIT 291

  Fly   268 PKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFNV 315
            |..|:||..||||:|...|...:.|.:...|:|........|.|||::
Human   292 PSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHI 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	131/289 (45%)
		Tas	12..299	CDD:223739	131/290 (45%)
AKR1E2	XP_011518017.1	ARA1	34..322	CDD:223729	131/289 (45%)
		Tas	42..314	CDD:223739	129/274 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730