Protein Alignment CG12766 and AKR1D1

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_005980.1
• Gene: AKR1D1 / 6718
• HGNCID: 388
• Length: 326
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 133/313 - (42%)
• Similarity: 187/313 - (59%)
• Gaps: 12/313 - (3%)

  Fly    12 NDGTHIQGIGLGTF----ASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVI 72
            :||..|..|||||:    ::.:|.|..:|..|||.||||||.||.|.||.|||.|:|:|||||.:
Human    13 SDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKV 77

  Fly    73 KREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEV 137
            :|||||...|||...|.||.|.....:||:.:.|||||||:|..|.::| .|| |:.|:|.||:.
Human    78 RREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK-PGD-EIYPRDENGKW 140

  Fly   138 ELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKL 200
            .....:...||.|||...|.||.||:||||||..||..:|  ...|.||:.||:|.||...|.||
Human   141 LYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKL 205

  Fly   201 IALCKKNGILVTAFSPLGRHN----AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIP 261
            :..|:::.|::||:||||...    ..:.:|..:.|..:.::..:|||:.||:|:|:.|:.|.:.
Human   206 LKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVV 270

  Fly   262 LPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            :|||.|.:||:|||.:|||.|..|:...:::.:...|............|||:
Human   271 IPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFH 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	129/296 (44%)
AKR1D1	NP_005980.1	AKR_AKR1D1-3	15..322	CDD:381335	130/308 (42%)