DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10357 and Pla1a

DIOPT Version :10

Sequence 1:NP_647821.2 Gene:CG10357 / 38435 FlyBaseID:FBgn0035453 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_598863.3 Gene:Pla1a / 85031 MGIID:1934677 Length:456 Species:Mus musculus


Alignment Length:261 Identity:87/261 - (33%)
Similarity:122/261 - (46%) Gaps:52/261 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 PSADVSLENVEQLSSVE-----SVKLIVHGYLGSCTHGS-IMPLRNAYTAQGYENVLVADWGPVA 95
            ||....:|....:.|.|     ..|:|:||:....|..| |....:|.......||:..||    
Mouse    61 PSCGQLVEEGSDIRSSEFNASLGTKVIIHGFRALGTKPSWIDKFISAVLRAADANVIAVDW---- 121

  Fly    96 NLDYPSSRL---AVKNVAQI-------LAKLLEEFLQRHGISLEGVHVIGHSLGAHIAGRIGRYF 150
              .|.|:.:   ||:||.::       |:||||     .|:|...:|:||.|||||:.|.:|.::
Mouse   122 --VYGSTGVYYSAVENVVKLSLEISRFLSKLLE-----LGVSESSIHIIGVSLGAHVGGMVGHFY 179

  Fly   151 NGSLGRVTGLDPALPLFSSRS-DDSLHSNAAQFVDVIHTDYPLFGDIRPRGTVDFYPNFGLAPQP 214
            .|.||::||||||.|.::..| ::.|.:..|.||:.||||....|...|.|.||::.|.| ..||
Mouse   180 KGQLGQITGLDPAGPEYTRASLEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGG-QDQP 243

  Fly   215 GCENVDVVAASKLLHEAYS---CSHNRAVMFYAESIGMPENFPAVSCSLTAI-----KSRRVEDC 271
            ||        ....|..|:   |.|.|||..|..::   ||    :|.|.|.     |:....||
Mouse   244 GC--------PAFFHAGYNYLICDHMRAVHLYISAL---EN----TCPLMAFPCASYKAFLAGDC 293

  Fly   272 L 272
            |
Mouse   294 L 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10357NP_647821.2 Pancreat_lipase_like 28..308 CDD:238363 87/261 (33%)
Pla1aNP_598863.3 Lipase 14..336 CDD:395099 87/261 (33%)

Return to query results.
Submit another query.