Protein Alignment CG10357 and PNLIPRP2

DIOPT Version :10

• Sequence 1: NP_647821.2
• Gene: CG10357 / 38435
• FlyBaseID: FBgn0035453
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_005387.3
• Gene: PNLIPRP2 / 5408
• HGNCID: 9157
• Length: 469
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 97/305 - (31%)
• Similarity: 134/305 - (43%)
• Gaps: 49/305 - (16%)

  Fly    56 KLIVHGYLGSCTHGSIMPLRNAYTAQGYENVLVADWGPVANLDYPSSRLAVKNVAQILAK---LL 117
            :.|:||:|..........:..........|.:..||...:...|..   ||:|:..:.|:   |:
Human    90 RFIIHGFLDKAEDSWPSDMCKKMFEVEKVNCICVDWRHGSRAMYTQ---AVQNIRVVGAETAFLI 151

  Fly   118 EEFLQRHGISLEGVHVIGHSLGAHIAGRIGRYFNGSLGRVTGLDPALPLFSSRSDD-SLHSNAAQ 181
            :....:.|.|||.|||||||||||.|...||...|.:||:||||||.|.|....:: .|..:.|.
Human   152 QALSTQLGYSLEDVHVIGHSLGAHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAV 216

  Fly   182 FVDVIHTD-YPL-----FGDIRPRGTVDFYPNFGLAPQPGC-ENV-----DVVAASKLLHEAYSC 234
            |||||||| .|:     ||..:..|.:||:||.| ...||| :||     |:....:.:....||
Human   217 FVDVIHTDSSPIVPSLGFGMSQKVGHLDFFPNGG-KEMPGCKKNVLSTITDIDGIWEGIGGFVSC 280

  Fly   235 SHNRAVMFYAESIGMPENFPAVSC-SLTAIKSRRVEDCLRE------------KSKTNTENANDY 286
            :|.|:..:|:.|:..|:.|....| |....:..:...|..|            |.||:...
Human   281 NHLRSFEYYSSSVLNPDGFLGYPCASYDEFQESKCFPCPAEGCPKMGHYADQFKGKTSAVE---- 341

  Fly   287 QTVFM--GEHVN-------RSATLYYYLETNG---APPYGQGRNS 319
            ||.|:  ||..|       .|.||....:.||   ...||...||
Human   342 QTFFLNTGESGNFTSWRYKVSVTLSGKEKVNGYIRIALYGSNENS 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10357	NP_647821.2	Pancreat_lipase_like	28..308	CDD:238363	91/289 (31%)
PNLIPRP2	NP_005387.3	Lipase	18..354	CDD:395099	87/271 (32%)
		Required for galactolipase activity. /evidence=ECO:0000269|PubMed:26494624	93..105		3/11 (27%)
		Required for galactolipase activity. /evidence=ECO:0000269|PubMed:26494624	257..279		3/21 (14%)
		PLAT_PL	357..469	CDD:238857	9/30 (30%)