Protein Alignment CG10357 and LIPI

DIOPT Version :10

• Sequence 1: NP_647821.2
• Gene: CG10357 / 38435
• FlyBaseID: FBgn0035453
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_001289927.1
• Gene: LIPI / 149998
• HGNCID: 18821
• Length: 460
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 95/276 - (34%)
• Similarity: 133/276 - (48%)
• Gaps: 40/276 - (14%)

  Fly    58 IVHGY--LGSCTHGSIMPLRNAYTAQGY---------ENVLVADWGPVANLDYPSSRLAVKNVAQ 111
            ::|||  :||      :||    ..|.:         .||:|.||...|. .:..:| ||||..:
Human    79 LIHGYRPVGS------IPL----WLQNFVRILLNEEDMNVIVVDWSRGAT-TFIYNR-AVKNTRK 131

  Fly   112 ILAKLLEEF--LQRHGISLEGVHVIGHSLGAHIAGRIGRYFNGSLGRVTGLDPALPLFSSRSDDS 174
            :...|....  |.:||.||:..|.||.||||||:|.:|:.|:|.|||:||||||.|.||.:...|
Human   132 VAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYS 196

  Fly   175 -LHSNAAQFVDVIHTDYPLFGDIRPRGTVDFYPNFGLAPQPGCENVDVVAASKLLHEAYSCSHNR 238
             |....|:||||||:|....|...|.|.:|||||.| ..||||.. .:.:..:.:    .|:|.|
Human   197 RLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGG-NKQPGCPK-SIFSGIQFI----KCNHQR 255

  Fly   239 AVMFYAESIGMPENFPAVSCSLTAIKSRRVE-----DCLREKSKTNT-ENANDYQTVFMGEHVNR 297
            ||..:..|:....||.:..|  .:.|..:..     ||.:|||.... ..|..::.|.......|
Human   256 AVHLFMASLETNCNFISFPC--RSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGR 318

  Fly   298 SATLYYYLETNGAPPY 313
            ......:|:|:|..|:
Human   319 PLRTTVFLDTSGTYPF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10357	NP_647821.2	Pancreat_lipase_like	28..308	CDD:238363	92/269 (34%)
LIPI	NP_001289927.1	Pancreat_lipase_like	41..309	CDD:238363	89/249 (36%)