Protein Alignment armi and Dna2

DIOPT Version :10

• Sequence 1: NP_647816.2
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_727386.1
• Gene: Dna2 / 31934
• FlyBaseID: FBgn0288690
• Length: 1100
• Species: Drosophila melanogaster
• Alignment Length: 1320
• Identity: 249/1320 - (18%)
• Similarity: 433/1320 - (32%)
• Gaps: 463/1320 - (35%)

  Fly    23 LDRENSFLDQKLMEEKMDQQLKANPNEINGV------------------LSNKIAELTHGLSEMD 69
            |:.:|:.:.....::|..:||..:.:|:..:                  :||...|||. ....:
  Fly    12 LENDNTDVTSSNPQKKFKEQLDFSSDEVENIDWGDNDDFDLALIAAMDSISNHRLELTK-WQRCE 75

  Fly    70 VSKESSCTARKGVITSL----DGDRGVIDKDVL-----FETKVAEDIIL----DLHVGCVV---- 117
            |.:......|||:...:    .||....|..:|     ...:|.:.:.|    |...||.|
  Fly    76 VVRLEQLPNRKGLKVHVKRISGGDPETADCQLLPPWNCMPMQVGDTVSLLGKWDPSAGCYVVDKE 140

  Fly   118 --------EYL---TFTTGEAMRVVKVKSILEHSWEDTSQKEIEKAVDNLKNE------KPTFFN 165
                    ::|   |..||...  .|.||:|:..:...........:..|.:|      :...|
  Fly   141 QGYCVSHPDFLISGTTVTGSLF--CKRKSVLQERFRGLDSGNSVMVIGTLVHELLQKVLRQKLF- 202

  Fly   166 TETRSVLGLISQRLASSIDVETEYGQ--LTVELDNIEMNFIPTNGDRVRLECNIQLDDGFVDKQG 228
             :.:.:...:.:.||||......|..  :.||:::..|.||                |..|.
  Fly   203 -DKKHIQSALQEMLASSSLAHLLYASNLIQVEMEDHLMKFI----------------DPIVS--- 247

  Fly   229 EILEVTKLFPTRIQEGEKCIVERVYVHMVVLGPETYILKTDLPTGTDLHLGDIVLADLIECQYSK 293
                    |..:..:||.         ..||.||.|        ...:|
  Fly   248 --------FVAQYVKGEP---------PSVLLPEVY--------RGQIH---------------- 271

  Fly   294 FTRRAIKITPLEKNFGATKLTQQSSMGSSGSGKAVTVTGVNRFITAELWQKESVSLKLTNNLNRT 358
                  :|..:|:|....:|      |..|                    |..||:|:.|
  Fly   272 ------EICDIEENLWVPQL------GLKG--------------------KVDVSVKVKN----- 299

  Fly   359 LRLESITVCNDSESQLSVVSPLESKEISSGSEITVTFEIHTQFLGEAIEKYVLNFDLL---KVRR 420
                        :.|...:.|||.|        |.......:..|:     :|.:.|:   :.|.
  Fly   300 ------------QRQREEIIPLELK--------TGRASFSMEHKGQ-----LLLYQLMHSAQGRD 339

  Fly   421 VFTVIVCKTKEEVAEAEKRMIAAEALMAPGRNSQERSRFYANQV--WCNKVDVIPGQQIVTKRRF 483
            ..:.::...||.:...          :|.|||.|.......|.:  |..:...||..:
  Fly   340 TQSGLLLYLKEGLLRE----------VASGRNEQRDLLMLRNDLAYWLTREVAIPASK------- 387

  Fly   484 VALRLGCFEVPKE------------------LRQICLTSERRQEMIKAIEQH-----YSFLTEPL 525
                    |.|.|                  ...||.:..::...::..:.|     ...|.|.|
  Fly   388 --------EDPLEQLPLPEPVYHHSACGNCAYNTICSSFAQKDSSLQLSDSHPLKKLMPQLLEHL 444

  Fly   526 S--IKTYMHRFRLLLHLEEIECFVNFRNYDRDRAHFLRDGEFLT-----LQIENLAERRPSLVIG 583
            |  ...|:..:..||.|||        .::|..:|.   ..|.|     .:.|.:|.|...||.|
  Fly   445 SEADHAYVQHWCGLLALEE--------QHNRQSSHV---RSFWTKDPAEREKEGIAIRHLKLVKG 498

  Fly   584 -----------DTLRVINPWSDPDSQTTKS------------------YEGIIHKVLFDRILLKF 619
                       .||. :...:||....:.|                  ..|.|..:...|:.|:.
  Fly   499 QEVILEEGRYRQTLE-LGEEADPSRDLSLSGFDLGEYVVISSTSRLAVAAGFIVSIEARRLDLRL 562

  Fly   620 HSSFQEKYNGEDYRLEFY----FSRYSFR-------------------------KQHHAISKIVG 655
            .....::|:.|.:.::.:    |:.::|.                         :||..:.||:.
  Fly   563 ERDLSQRYSEETFIIDKHDSQSFATFNFTNLGMLLSEGERFQELRDIIVAKKPPEQHKVLPKIIL 627

  Fly   656 VMGEDFLFPSKVTKRENPQLDVYMKDDDMYLYDSKLEWYNQSLNSIQKRAVFNILRGEAENIPYV 720
            ..|...|.                                 :||.:|:.|.   ||....:...:
  Fly   628 TKGAPILL---------------------------------NLNKVQQNAA---LRALTTSSHLL 656

  Fly   721 LFGPPGSGKTMTLIETLLQLVRNLPGARILVGTPSNSSADLVTKRLIDSKALLQGDFIRLVSYNQ 785
            :.|.||:|||.||: .|::|: :|.|..:|:...::|:.|.:..||:....    ..:||.|.::
  Fly   657 IKGLPGTGKTQTLV-ALVRLL-HLLGKSVLITAQTHSAVDNLIMRLLPFGL----PMMRLGSGSR 715

  Fly   786 VEKDLIPPEIMSYCATSDVGAVGSCEDKMMVTESGLKLRCQAKFIGTHRITISTCTTLGNFLQLG 850
            :.|.|  .||.....|.|...|...|                |.:|...|...||...|:.|
  Fly   716 IHKQL--EEISEERLTKDCKTVEELE----------------KALGQPSIVGVTCLGCGHPL--- 759

  Fly   851 FPAGHFTHVLFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLE 915
            |....|.:.:.|||.|..:|..:.|::..:|    .||.|||.||..||.|:.|.:.|...:..:
  Fly   760 FQRRQFDYCIVDEATQVLQPTVLRPLIHCSK----FVLVGDPEQLPPIVRSKEARQRGADETLFQ 820

  Fly   916 RLLERSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDEL------------- 967
            ||        |.::          ....|...||...:|..:.:.|.|..:|
  Fly   821 RL--------DSEK----------ATAVLSLQYRMNKTITRLANELTYGGDLKCASDEVSGARFE 867

  Fly   968 IPVLSEKDSRESRLLSK---------------LRC---VFESEKDIPQAHGTFFYGIIGENRQNN 1014
            :.:|:|......|.|:.               .||   |:.|::.:......       |...:.
  Fly   868 VELLNEAPRWVQRALTTHLEQAVTLINTGDCLERCQEFVYASQRLVDTCSSI-------EQSFSE 925

  Fly  1015 DSPSWFNPQEVREV----------------FLMTIALY--RANVTADQIGIITPYQKQVKMLRSM 1061
            |.      .|:|::                .:|.:..|  ::...|.:||:|.||:.||::.:.:
  Fly   926 DK------DEIRKLTSKKRVSKYTNYCEAGIVMHLLRYLLKSGYEASRIGVIAPYRAQVELFKKL 984

  Fly  1062 F--IGTDVVMPKIGSVEEFQGQERDIILISTVRSSEEILRMDARFSLGFVRCSKRLNVAVSRARA 1124
            .  :.||:   :..:|::|||:::::|:.|..::..:...|:.......:...:||.||::||:.
  Fly   985 ASKLDTDL---ECNTVDQFQGRDKNLIIYSCSKTGGDFSDMERSREAEILEDQRRLTVAITRAKN 1046

  Fly  1125 MMIIFGNPHLLAVDECWRQL 1144
            .:|:.|:...|.....:|||
  Fly  1047 KLILLGDIKCLEQYGPFRQL 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_647816.2	DEXXQc_Mov10L1	697..949	CDD:350836	66/251 (26%)
		DNA2	<829..1148	CDD:440729	80/367 (22%)
Dna2	NP_727386.1	DNA2_N-like	153..378	CDD:411722	61/360 (17%)
		DEXXQc_DNA2	636..836	CDD:350799	66/251 (26%)
		AAA_12	815..1055	CDD:463780	49/273 (18%)