Protein Alignment armi and dbl8

DIOPT Version :10

• Sequence 1: NP_647816.2
• Gene: armi / 38427
• FlyBaseID: FBgn0041164
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_596055.1
• Gene: dbl8 / 2540523
• PomBaseID: SPBC29A10.10C
• Length: 1944
• Species: Schizosaccharomyces pombe
• Alignment Length: 1467
• Identity: 279/1467 - (19%)
• Similarity: 518/1467 - (35%)
• Gaps: 475/1467 - (32%)

  Fly    40 DQQLKANPNEINGVLSNKIAELTHGLSEMDVSKESSCTARKGVITSLDGDRGVIDKDVLFETKVA 104
            ||.|:....|::..|:.|..||   ...:::..|.|...|            :|.|  :||.::.
pombe   416 DQSLQNKVFELHSTLAIKFDEL---FRLLNLENEESVEWR------------LIKK--VFEYRLN 463

  Fly   105 EDIILDLHVGCVVEYLTFTTGEAMRVVKVKSILEHSW---EDTSQKE-------IEKA------V 153
            .|:.:.....|  .||.......:.:..|....::.|   ::..::|       :.:|      :
pombe   464 LDLYILKQFYC--HYLDRNRKPPLNIKSVSESFKNFWVYLQNVFREEKFFMVRIVFRACSTVCLI 526

  Fly   154 DNLKNEKPTF-FNTETRSVL-GLISQRLASSIDVETEYGQLTVELDNI----------EMNFIP- 205
            |.|..:|... |.::..:.| |.::  ..|.:.::|:...|:.:...:          .:.|.|
pombe   527 DKLPPKKVDIPFKSDFENALNGFVA--TFSEMLIQTQCWHLSAQTQLVSNPLTFRGIFSLVFSPI 589

  Fly   206 ---TNGDRVRLECNIQLDDGFVDKQGEILE-------------VTKLFPTRIQEGEKCIVERVYV 254
               :.|. :.:..:|.|.|..||..||:|.             :.:....|...|.|.|   ||.
pombe   590 LEISTGS-ISIIKSISLSDSVVDTIGELLRSQFSNTLNSSCYVLLQWLKVRNFGGAKHI---VYF 650

  Fly   255 HMVVLGPETYILKTDLPTGTDLHLGDIV-----LADLIECQYSKFTRRAIKIT--PLEKNFGATK 312
            :.:::  .|.....|..|..|......|     |.:..|..:..||...|.:.  |:........
pombe   651 NKLII--NTIFDSVDGLTSKDATFAKQVEKKESLKNFWESLWKFFTHFFIVLPTWPVHDKDNLVD 713

  Fly   313 LTQQS---------------------------SMGSSGSGKAVTVTGVNRFITAELWQKESVSLK 350
            |.:.:                           .:.::..|.|:.:...:..:|...|.|.:.|..
pombe   714 LMRDTLDFCDMLINIFEEVNGFIFGLSDNDIKIVSANDKGSALAMCIADSLVTVSYWLKLTDSSL 778

  Fly   351 LTNNLNRTLRLESITVCNDSESQLS--VVSPLESKEISSGSEITVTFEIH-------TQFLGE-- 404
            ||:.:....::  :.:|...|..:|  |:..:....|:|..:..:||...       |.:|.|
pombe   779 LTSVVKVICKM--LKICKKLECPISQNVIDIIHRASITSDEQTILTFTEREDLFISLTPYLSEDV 841

  Fly   405 ----------AIEKYVLNFDLLKVRRVFTVIVCKTKEE--VAEAEKRMIAAEALMAP---GRNSQ 454
                      .:|..:.:.|...:.:..|:.:.|...|  ::.:...::..:|:.|.   .||:|
pombe   842 LNHSPFNDTNTLETKLQSDDRGLLSKDQTIGIAKKLPESNISTSNHFLLPPKAISASKAINRNAQ 906

  Fly   455 ERSRFYANQVWCNKVDVIPGQQIVTKR-------------RFVALRLGC-FEVPKELRQICLTSE 505
            :          ...::.:..:|..|:|             ..::.:|.. ..:||.|:::.....
pombe   907 K----------SQNLNFLKSKQETTQRIRESAKVPRTSAGNHLSEKLNSDNHIPKALQKLDSADP 961

  Fly   506 RRQEMIKAIEQHYSFLTEP-------------------------LSIKTYMHRFRLLLHLEEIEC 545
            .|:..:....:.||   .|                         |:.:...|..:.|....:|:
pombe   962 IRKPSLLHTSKSYS---NPDDKNTSTSDEDTSESEEESSNGLFSLAREANSHASKSLPQRRQIQ- 1022

  Fly   546 FVNFRNY-DRDRAH--FLRDGEFLTLQIENLAERRPSLVIGDTLRVI---NPWSDPDSQT----- 599
            |::|.:. .::..|  .||..   |.|...||..|.:..:.:..:||   ||.:|..|.:
pombe  1023 FLDFDSLKTKNVVHPTQLRRN---TQQSAQLARLRLNPDVQEFYKVILGWNPLADSFSASNVEMQ 1084

  Fly   600 ----------TKSYEGIIHKVLFDRILLKFHSSFQEKY-----------NGEDYRLEFYFSRYSF 643
                      :.:||.:...:||.....:..|:.:||.           :..|..::.||:..|
pombe  1085 CVQAKFTYNDSNAYEKVFKPMLFHECWAQVKSAVEEKQYPPIDLILNTRSTVDNFVDIYFTSCS- 1148

  Fly   644 RKQHHAISKIVGVMGEDFLFPSK---------------------VTKRENPQLDVYMKDD--DMY 685
                  .:::..:...|....||                     ..|:|:.:|.:.|..:  |:.
pombe  1149 ------PTEVSFLSDTDICLLSKSQSSGDTNNPKSFQLCKIQSISRKKESLELCLRMNIESIDLQ 1207

  Fly   686 LYDSKLEWYNQSL----NSIQKRAVFNILR--------------------------------GEA 714
            .|...:.:..|.|    .|:::.|....||                                |..
pombe  1208 EYAPNIRFTAQKLFNATTSLREFAALKSLRHLPLSQRILDANVTRLPSNFTDDKKQKIMKSYGVN 1272

  Fly   715 ENIPYVLF------------GPPGSGKTMTLIETL----------LQLVRNLPGA-------RIL 750
            |...|.::            ||||:|||.|::..:          ||.  |:||.       :||
pombe  1273 EPQAYAIYASSVNDGFTLIQGPPGTGKTKTILGMIGAVLTSSSQGLQF--NVPGQTRKTSKNKIL 1335

  Fly   751 VGTPSNSSADLVTKRL---------------------------------IDSKALLQGDFIRL-- 780
            :..|||::.|.:..|:                                 ::.:.:.|.:...|
pombe  1336 ICAPSNAAIDEILLRIKAGVYDHEGIKFFPKVIRVGFGDSISVHAKEFTLEEQMIKQMELTNLKK 1400

  Fly   781 -----------VSYNQV--EKDLIPPEIMSYCATSDVGAVGSCE------DKMMVTES------- 819
                       ..|:.:  ::|.:..::..:.:|....::...:      .|.|:.:|
pombe  1401 DQEANNSSDTRKKYDSIIKKRDSLREDLEKFRSTGKNSSILEAQLREITKQKNMLEQSLDDMRER 1465

  Fly   820 ---------GLKLRCQAKFIGTHRITISTCTTLGNFLQLGFPAG-HFTHVLFDEAGQCTEPETMV 874
                     .||.:.|.:.:....|..:|.:..|:.|.|.  || .|..|:.|||.|..|..:::
pombe  1466 QRSTNRNLDVLKKQIQNQLLQEADIVCATLSASGHELLLN--AGLTFRTVIIDEAAQAVELSSII 1528

  Fly   875 PIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLERS---------PYR--KDLQ 928
            |   |.......|:.|||.||...|.|:.::|.|:|.|...|:.::.         .||  .::.
pombe  1529 P---LKYGCESCVMVGDPNQLPPTVLSKTSAKFGYSQSLYVRMFKQHNESACLLSIQYRMNPEIS 1590

  Fly   929 RFPESSGYNPLVLTKLLYNYRAL--PSIMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFES 991
            |||          :|..||.:.|  |::.::.||.:::|
pombe  1591 RFP----------SKFFYNSKLLDGPNMSAVTSRPWHED-------------------------- 1619

  Fly   992 EKDIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMTIALYRANVTAD---QIGIITPYQK 1053
                ||.....|:.:.|....:| |.|.:|.:|...:.|:...|.:..:..|   :||::|||:.
pombe  1620 ----PQLGIYRFFNVHGTEAFSN-SKSLYNVEEASFILLLYERLIQCYLNIDFEGKIGVVTPYRS 1679

  Fly  1054 QVKMLRSMFIGTDVVMPKIGS----------VEEFQGQERDIILISTVRSSEEILRMDARFSLGF 1108
            ||:.|||.|      ..|.||          |:.|||||:|||:.|.||||     |..  .:||
pombe  1680 QVQQLRSQF------QRKYGSIIFKHLDIHTVDGFQGQEKDIIIFSCVRSS-----MSG--GIGF 1731

  Fly  1109 VRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLI 1145
            ::..:|||||::||::.:.|.||...|..::.:..||
pombe  1732 LQDLRRLNVALTRAKSSLYIVGNSKPLMQEDIFYSLI 1768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
armi	NP_647816.2	DEXXQc_Mov10L1	697..949	CDD:350836	76/398 (19%)
		DNA2	<829..1148	CDD:440729	98/344 (28%)
dbl8	NP_596055.1	SEN1_N	75..784	CDD:432746	69/394 (18%)
		TIGR00376	1219..1780	CDD:273041	137/611 (22%)
		AAA_12	1560..1756	CDD:463780	69/249 (28%)