Protein Alignment kst and Dyb

DIOPT Version :10

• Sequence 1: NP_001097492.2
• Gene: kst / 38418
• FlyBaseID: FBgn0004167
• Length: 4337
• Species: Drosophila melanogaster
• Sequence 2: NP_001097287.1
• Gene: Dyb / 36362
• FlyBaseID: FBgn0033739
• Length: 816
• Species: Drosophila melanogaster
• Alignment Length: 858
• Identity: 179/858 - (20%)
• Similarity: 273/858 - (31%)
• Gaps: 282/858 - (32%)

  Fly  3421 AAKLGEIYPDAKEHIEVKRDETVEAWTDLKEKTAARKNKLSQAE-QLQSYFDEYRDLIAWINEML 3484
            |:||..|......|:       |:.|..::   |.|:|.|:..| |.:........|::.:...|
  Fly    29 ASKLRYIQKSTNLHL-------VDIWNVIE---AFRENGLNTLEPQSEVSVARLETLVSSLYHNL 83

  Fly  3485 AK--ITAPEL-ANSVAGA---ELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVED 3543
            .|  .||.:: .:|.||.   .||.|.|.|:..:||......|.......:|:.:..::..::.|
  Fly    84 NKRLPTAQQVPVDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISD 148

  Fly  3544 KIKVLQA--RHELLKHTLNKRREIYEL-------NLDTQLFLKDAEI-LEQWISS--REPQLKDT 3596
            ....|.|  ..|.|:..|.....:||.       .|:.::|..:.:: :..::::  .||
  Fly   149 GAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENKVTVNDFMATLMSEP----- 208

  Fly  3597 KLGDS----IPQVEDLLRRHEDFEKTVAA--QEEKF-------QAIKRITMLEQLF-------RH 3641
              |.|    :|.|..|.........||.:  .:|.|       |......:.::.|       .|
  Fly   209 --GPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNH 271

  Fly  3642 QLEQE--------KISK-----LQEKERLEKERLEQLKQRELQRLADERRRAEKQHEHRQNAASQ 3693
            |.:.|        ..||     |::..|...|:..|:    |.|..|:                .
  Fly   272 QNDHEVKEYSSYKSPSKQIGHSLRKSFRCVPEKTVQV----LPRFPDQ----------------P 316

  Fly  3694 EKTPIFS---SPMVTPAQTSGPQSPALSQVQLRPPFGDDNEHLALQKS-------------SSSG 3742
            |||...|   .|...|:.........|......|..|...:|....:|             |:||
  Fly   317 EKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPGLPGQHGLFDRSSTLDSRATGRSLDSASG 381

  Fly  3743 MFGDRLRR-GSADAN------VKRAESMKVQPKQA------KRTPSFTTRRRAQS------FRKN 3788
            ..|..:.| .:|.||      :.|..:...|..:|      ..||..|...|||.      ..||
  Fly   382 TAGTTMSRVAAASANDEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNSRAQRELIAQLESKN 446

  Fly  3789 QKGEGFDLPPVEIQGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQKTATAP 3853
            :          ||...:.|....|...:.||                     ||..|
  Fly   447 K----------EIMREIARLRRQQETEQMAP---------------------ENPAL-------- 472

  Fly  3854 VNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKISFHASLPPNMQLLSYDE 3918
            :|.|.|..:|..:.            :|        .|..|.|..|::.        .||.....
  Fly   473 INELRALRQRKGEL------------EG--------HLGALQDSRRQLM--------EQLEGLMR 509

  Fly  3919 SMKQQSSSSPDIKVTSSVESPVSSRNSSPDSQR---RTSGAQVLDGTATPQMAFLQRQMQQ---- 3976
            .:|.|.::||.           |:.||||.|.:   ...||.:| || :|..|...:||||
  Fly   510 MLKNQQTASPR-----------STPNSSPRSGKSPPMPGGAGIL-GT-SPMSALHAQQMQQHPMA 561

  Fly  3977 -----------QQQQQQSQPSSPTGGFDQKPPIPPRGAAPVASHRQSQENLVVMRNRQSSNDLQQ 4030
                       ||||||:                 .|..|.:..:..|.|       |.|:|::.
  Fly   562 GGVRASQQQLLQQQQQQA-----------------HGHGPFSQSQLEQLN-------QISSDMRS 602

  Fly  4031 SATLPAGLTGVQQNGNGKDDNALLTRNSEARQSDNPPPLPTTMPPVGGQHQHPQNSHSHQNQH-- 4093
            :..           .||               |..|||:.||............|..|:||.:
  Fly   603 AFA-----------ANG---------------SATPPPMRTTTATANVSAIPSLNPISNQNPNLN 641

  Fly  4094 -QAQVQQRINAFNAAASQQHQPDYFNNNTARQQ---PQRIPSGRIDSTRKFIEMEAHNNNGGTSS 4154
             .|::.:..:...:|.|  |.....|....|.|   ||  |:..|...|..:.:|..:..||.|.
  Fly   642 PDAELNEAADHLTSAIS--HMVSDLNAGRGRAQQLGPQ--PASSIPQARFIMPLEFRHIEGGESE 702

  Fly  4155 SPKRSTINYSSSG 4167
            ...:...|....|
  Fly   703 DSSQCECNDCECG 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kst	NP_001097492.2	CH_beta_spectrin_rpt1	61..176	CDD:409042
		CH_beta_spectrin_rpt2	196..302	CDD:409043
		SPEC	450..640	CDD:238103
		SPEC	658..832	CDD:238103
		SH3	885..935	CDD:214620
		SPEC	1030..1236	CDD:238103
		SPEC	1134..1341	CDD:238103
		SPEC	1343..1551	CDD:238103
		SPEC	1449..1658	CDD:238103
		SPEC	1555..1764	CDD:238103
		SPEC	1765..1975	CDD:238103
		SPEC	1873..2080	CDD:238103
		SPEC	1979..2185	CDD:238103
		SPEC	2188..2402	CDD:238103
		SPEC	2407..2618	CDD:238103
		SPEC	2514..2725	CDD:238103
		SPEC	2726..2934	CDD:238103
		SPEC	2935..3145	CDD:238103
		SPEC	3042..3251	CDD:238103
		SPEC	3149..3357	CDD:238103
		SPEC	3359..3567	CDD:238103	36/154 (23%)
		SPEC	3465..3680	CDD:238103	53/265 (20%)
		PH_beta_spectrin	3801..3904	CDD:269975	17/102 (17%)
Dyb	NP_001097287.1	EFh_DTN	45..205	CDD:320002	34/162 (21%)
		EF-hand-like motif	45..86	CDD:320002	9/43 (21%)
		EF-hand-like motif	95..129	CDD:320002	11/33 (33%)
		EF-hand-like motif	135..171	CDD:320002	7/35 (20%)
		EF-hand-like motif	182..205	CDD:320002	2/22 (9%)
		ZZ_dystrophin	232..280	CDD:239074	9/47 (19%)
		CwlO1	376..691	CDD:443091	97/448 (22%)
		ClpA	<430..>514	CDD:440308	26/150 (17%)