Protein Alignment: Hsp83 and enpl-1

• Sequence 1: NP_001261362.1
• Gene: Hsp83
• FlyBaseID: FBgn0001233
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001255536.1
• Gene: enpl-1
• WormBaseID: WBGene00011480
• Length: 760
• Species: Caenorhabditis elegans
• Alignment Length: 725
• Identity: 326/726 (45%)
• Similarity: 469/726 (65%)
• Gaps: 39/726 (5%)

  Fly     4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKL 68
            :||...||||:.::|.||||:.|.|||||||||||||||||||||..|||||.:|...:|:.:|:
 Worm    60 KAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKI 124

  Fly    69 IPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADIS-----MIGQFGVGFYS 128
            ..::....|.|.|||:|||:.||:|||||||:|||..|:..|...|..|     :|||||||||:
 Worm   125 KADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYA 189

  Fly   129 AYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRAD-NSEPLGRGTKIVLYIKEDQTDYLEESKIK 192
            |:||||:|.||:|||||:||:|||.: .|||:..| ....|.|||:|.||:||:..|:||...:|
 Worm   190 AFLVADRVVVTTKNNDDDQYIWESDS-ASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLK 253

  Fly   193 EIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDK 257
            .:|:|:||||.:.|.|...|....|           |..|::...|::..:|:          :|
 Worm   254 NLVHKYSQFINFDIFLWQSKTEMVE-----------EAVEEEPATTEDGAVEE----------EK 297

  Fly   258 DAKKKKTIKEKYTED-EELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLE 321
            :.||.|.: ||.|.| |::|..||||.|.|:.:.::||.:||||:|.|.|:.|:..|||.||::.
 Worm   298 EEKKTKKV-EKTTWDWEKVNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVS 361

  Fly   322 FRALLFIPRRTPFDLFENQ-KKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISR 385
            ||::|::|:::|.|:|:|. |...|||||||||||.|:..|::|:||:|::|:|||:|||||:||
 Worm   362 FRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSR 426

  Fly   386 EMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRF 450
            |.|||:|:||||:|.||:|.::::::|  |...:..|:.:||.|:||||.||.:||.:||..|||
 Worm   427 ENLQQHKLLKVIKKKLVRKVLDMLKKL--DGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRF 489

  Fly   451 HTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVI 515
            .:|...|...:||.||.|||:.|..:|::.|.|:.:|..|.||||:.|:|:||:::||.:|||.|
 Worm   490 QSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCI 554

  Fly   516 QHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMK-SILDNKVEKVVVSNRLVD 579
            |.:.||:.|:..:|.|||:.:.:.|..|:..:..:.:|:.|...:| :.|.:.:||.|||.|||.
 Worm   555 QAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKETALKDLIEKAVVSQRLVK 619

  Fly   580 SPCCIVTSQFGWSANMERIMKAQA---LRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKND 641
            ||..:|.|.:|||.|||||||:||   .:|.....|...||..||||.||:::.|.::..|.:.|
 Worm   620 SPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINPRHPVIKELLKRVTASEED 684

  Fly   642 KAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDD-AQSAGDAPSLVE 705
            ........|||||:.|.|||||......|.||..:::..|.:.:|..:.|:. .:.|...|...|
 Worm   685 TTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLRQSLDVSQDAQVETEQHIEEAEPEPEAAE 749

  Fly   706 DTE-DASHME 714
            :|. :..|.|
 Worm   750 ETTIEEEHSE 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp83	NP_001261362.1	PTZ00272	6..717	CDD:240341	325/724 (45%)
		HATPase_c	28..179	CDD:214643	91/157 (58%)
		HSP90	184..706	CDD:278607	218/529 (41%)
enpl-1	NP_001255536.1	PRK05218	59..724	CDD:235366	317/689 (46%)
		HATPase_c	84..242	CDD:214643	93/159 (58%)
		HSP90	245..735	CDD:278607	215/514 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D174605at33208
OrthoFinder	1	1.000				FOG0000421
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_126623
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910