DRSC/TRiP Functional Genomics Resources

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Protein Alignment Alg2 and piga

DIOPT Version :10

Sequence 1:NP_647772.1 Gene:Alg2 / 38374 FlyBaseID:FBgn0035401 Length:424 Species:Drosophila melanogaster
Sequence 2:NP_001119918.1 Gene:piga / 791759 ZFINID:ZDB-GENE-040426-1086 Length:487 Species:Danio rerio


Alignment Length:445 Identity:96/445 - (21%)
Similarity:169/445 - (37%) Gaps:109/445 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 FLHPDLGIGGAERLVVDAALALKERGHQVSFLTNHHDSTHCFKETADGTFPVHVVGD-----WLP 65
            |.:|::  ||.|..:...:..|.|:||:|...|                   |..||     :|.
Zfish    45 FFYPNM--GGVESHIYQLSQCLIEKGHKVVIAT-------------------HAYGDRRGIRYLT 88

  Fly    66 RGLFGRFYAICAYLRMLY-AAIYASFFMPQREQVDVVVCDLISVCIPVLRFAPHRPKVLFYCHFP 129
            .||  :.|.:  .|:::| .:...:.|    ..:.::.|..:..||.::.  .|..   |.....
Zfish    89 NGL--KVYYL--PLQVMYNQSTSTTCF----HSLPLLRCIFVRECITIVH--AHSS---FSAMAH 140

  Fly   130 DQLLSSREGLLKRLYRLPINWLEEHTI-GLAD--KVLVNSKFTLRVFQDTFRRLSTVPDVLYPSL 191
            |.|..::...|..::       .:|:: |.||  .||.|...|:.:. ||    :.:..|.|.| 
Zfish   141 DALFHAKTMGLNTVF-------TDHSLFGFADLSSVLTNKLLTVSLC-DT----NHIVCVSYTS- 192

  Fly   192 HTQYFDQMQKKLEQRSALLDEPVHPRVPLNAFIYLDINRYE-RKKNHALAL---------HSLRL 246
                     |:.....|.||..:...:| ||....|..... |:.|..:.:         ..:.|
Zfish   193 ---------KENTVLRATLDPEIVSVIP-NAVDPTDFTPDPCRRDNSKITIVVISRLVYRKGIDL 247

  Fly   247 LGDMLPATDFKRCRLIIAGGYDTRCM----ENVEHFAELEHLTEELKLQDHVVLLRSPTDEEKCR 307
            |..::|.         :.|.:...|.    |..:... ||.:.|:.:|.|.|.||.:...::...
Zfish   248 LSGIIPE---------LCGRHPDLCFLIGGEGPKRII-LEEVREKYQLHDRVRLLGALDHKDVRD 302

  Fly   308 LLFAAHCLLYTPENEHFGIVPLEGMYCSKPVVALNSGG-----PTE--TVVSTSTGFLCEKTEKS 365
            :|...|..|.|...|.|.:..:||..|...||:...||     |.|  |:...|...||:..|  
Zfish   303 VLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPNELVTLCGPSVCSLCDGLE-- 365

  Fly   366 FGGAMLQLFRDEQLRVKMGDQGHKRVQQKFSFQAFADR----LNGIIRD-LVPIS 415
               .:::..|..  .|:.....|::|:..::::..|:|    .|.:.|: ::|:|
Zfish   366 ---TVIKKIRSG--NVESPAAIHRKVRTLYTWRNVAERTEKVYNRVCREPVLPLS 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Alg2NP_647772.1 GT4_ALG2-like 2..404 CDD:340834 92/431 (21%)
pigaNP_001119918.1 GT4_PIG-A-like 38..437 CDD:340827 96/445 (22%)

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