Protein Alignment Alg2 and ALG1L2

DIOPT Version :10

• Sequence 1: NP_647772.1
• Gene: Alg2 / 38374
• FlyBaseID: FBgn0035401
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001129624.1
• Gene: ALG1L2 / 644974
• HGNCID: 37258
• Length: 215
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 45/205 - (21%)
• Similarity: 64/205 - (31%)
• Gaps: 71/205 - (34%)

  Fly   212 EPVHPRVPLNAFIYLDINRYERKKNHALA--LHSLRLLGDMLPATDFKRCRLIIAGGYDTRCMEN 274
            ||..|....:||.       ||.....|.  ||              :|..|:::.
Human    46 EPEDPDTERSAFT-------ERDSGSGLVTRLH--------------ERPALLVSS--------- 80

  Fly   275 VEHFAELEHLT---EELKLQDHVVLLRSPTDEEKCRLLFAAH------CLLYTPENEHFGIVPLE 330
             ..:.|.|.||   :.|.....|:..:.|..|...||:...|      |:   |..|..|:.||.
Human    81 -TSWTEFEQLTLDGQNLPSLVCVITGKGPLREYYSRLIHQKHFQHIQVCI---PWLEGRGLPPLL 141

  Fly   331 G-----------------------MY-CSKPVVALNSGGPTETVVSTSTGFLCEKTEKSFGGAML 371
            |                       |: |..|..|:|.....|.|.......:.|.:|:.  .|.|
Human   142 GSVDLDVCLDTSSSGLDLPMKVVDMFRCCLPACAVNFKCLHELVKHEENRLVFEDSEEL--AAQL 204

  Fly   372 QLFRDEQLRV 381
            |.|.|..|::
Human   205 QYFADAFLKL 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alg2	NP_647772.1	GT4_ALG2-like	2..404	CDD:340834	45/205 (22%)
ALG1L2	NP_001129624.1	Glycosyltransferase_GTB-type	<8..206	CDD:471961	41/195 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..66		7/26 (27%)