Protein Alignment Alg2 and ALG11

DIOPT Version :10

• Sequence 1: NP_647772.1
• Gene: Alg2 / 38374
• FlyBaseID: FBgn0035401
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001004127.2
• Gene: ALG11 / 440138
• HGNCID: 32456
• Length: 492
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 105/452 - (23%)
• Similarity: 188/452 - (41%)
• Gaps: 92/452 - (20%)

  Fly     4 VLFLHP--DLGIGGAERLVVDAALALKERGHQVSFLTNHHDSTHCFKETADGTFPVHVVGDWLPR 66
            :.|.||  :.| ||.||::..|..||:::..:..::....|              |:|.|..:..
Human    65 IAFFHPYCNAG-GGGERVLWCALRALQKKYPEAVYVVYTGD--------------VNVNGQQILE 114

  Fly    67 GLFGRFY------AICAYLRMLYA---AIYASFFMPQREQVDVVV-CDLISVCIP-----VLRFA 116
            |.|.||.      ....:||..|.   ::|..|.:..:....:.: .:.:..|:|     .:.:|
Human   115 GAFRRFNIRLIHPVQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYA 179

  Fly   117 PHRP--------KVLFYCHFP---DQLLS---------------SREGLLKRLYRLPINWLEEHT 155
            ...|        :|..|.|:|   ..:||               :|...|.:: :|...:|....
Human   180 FTLPLFKYIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKV-KLIYYYLFAFI 243

  Fly   156 IGL----ADKVLVNSKFTLRVFQDTFRRLSTVPDVLYPSLHTQYFDQMQKKLEQRSALLDEPVHP 216
            .||    :|.|:|||.:||......: ::....:::||....|.|             ||.|:|.
Human   244 YGLVGSCSDVVMVNSSWTLNHILSLW-KVGNCTNIVYPPCDVQTF-------------LDIPLHE 294

  Fly   217 RVPLNAFIYLDINRYERKKNHALALHSLRLLGDMLPATDFKRCRLIIAGGYDTRCMENVEHFAEL 281
            :......:.:.:.::..:|||.|.:.:...|.:..........:|::.||  .|..::.....:|
Human   295 KKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESPPSLKLVLIGG--CRNKDDELRVNQL 357

  Fly   282 EHLTEELKLQDHVVL-LRSPTDEEKCRLLFAAHCLLYTPENEHFGIVPLEGMYCSKPVVALNSGG 345
            ..|:|:|.:|::|.. :..|.||.| ..|..|...|:|..||||||..:|.|.....::|.||||
Human   358 RRLSEDLGVQEYVEFKINIPFDELK-NYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGG 421

  Fly   346 PTETVV----STSTGFLCEKTEKSFG---GAMLQLFRDEQLRVKMGDQGHKRVQQKFSFQAF 400
            |...:|    ...||||.| :|:.:.   ..:|.:..:::|:::   :..:....:||.|.|
Human   422 PKLDIVVPHEGDITGFLAE-SEEDYAETIAHILSMSAEKRLQIR---KSARASVSRFSDQEF 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alg2	NP_647772.1	GT4_ALG2-like	2..404	CDD:340834	105/452 (23%)
ALG11	NP_001004127.2	GT4_ALG11-like	63..480	CDD:340835	105/452 (23%)