DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16753 and SLX9

DIOPT Version :9

Sequence 1:	NP_647764.1	Gene:	CG16753 / 38365	FlyBaseID:	FBgn0035393	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_478070.1	Gene:	SLX9 / 85395	HGNCID:	15811	Length:	230	Species:	Homo sapiens

Alignment Length:	177	Identity:	45/177 - (25%)
Similarity:	85/177 - (48%)	Gaps:	29/177 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KTKKNVRAKAKSVVGAAKQKAQDMKAKLREDRLLHKTLTPKKTTTKKEKSEAKHKKLLKRFAEAR 67
            |.:.:||:......|.|...|:.:.:..|....  ||:.|     ||||.:.:.::.|::. ||.
Human    66 KLELDVRSVTSVRRGEAGSSARSVPSIRRGAEA--KTVLP-----KKEKMKLRREQWLQKI-EAI 122

  Fly    68 KKRKEEH---KNREKTKVVGDLKPLRDALPSLQDI----YKLVKTKQKDVSEGAALTEPEVRLSA 125
            |..:::|   :.|..|.|||||.|||||||.|..:    .:..::::.:....:.|:    |:||
Human   123 KLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELS----RMSA 183

  Fly   126 NEK---IRKKRTEMVNTVKSFEKLIKDKNFKKNPREVIAAHVRNKYQ 169
            .::   :.::||.       |::|:....::.:|...|...:..:.|
Human   184 AQRQQLLEEERTR-------FQELLASPAYRASPLVAIGQTLARQMQ 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16753	NP_647764.1	SLX9	54..167	CDD:291986	30/122 (25%)
SLX9	NP_478070.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		SLX9	99..221	CDD:317712	37/138 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..187		4/35 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007794
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108134
Panther	1	1.100	-	-	LDO	PTHR31109
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10237
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.900