Protein Alignment FMRFaR and frpr-6

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_872220.1
• Gene: frpr-6 / 353447
• WormBaseID: WBGene00017661
• Length: 349
• Species: Caenorhabditis elegans
• Alignment Length: 365
• Identity: 93/365 - (25%)
• Similarity: 174/365 - (47%)
• Gaps: 64/365 - (17%)

  Fly    94 WTRICEDVYNPLLENNRIEFWVCGVLINIVGVLGILGNIISMIILSRPQMR-SSINYLLTGLARC 157
            |......:|.|::                  ::|::||.:|:.:.:.|.|| |::.:||..|:.|
 Worm     6 WPEYVSMIYLPII------------------LVGLVGNGLSLYVYTTPNMRKSTVAFLLYSLSIC 52

  Fly   158 DTVLIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAV---FPIGMIAQTASIYMTFTVTLERY 219
            |..:::.::.|:.| |..|...:.:|.::....||:.:.   :|:.|.|:|||:|:...:|:||:
 Worm    53 DIFVLLFALPLYSI-SYLPIWDNVYGAWSMRRMFIAFSTKFFYPLCMTAKTASLYIMVVITVERW 116

  Fly   220 VAVCHPLKARALCTYGRAKIYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPSRLRRS 284
            :|||.||:....||:..:....|..:.||:..|.|:|:|     |.....|.:.:..:...|...
 Worm   117 IAVCRPLQVHIWCTFKNSVRIVIAIITFSIILNFPKFFE-----YQIGYSDALGYWPKRGILDAE 176

  Fly   285 ETYINIYIHWCY---------LIVNYIIPFLTLAILNCLIYRQVKRANRERQRLSRSEKREIGLA 340
            |       ||.|         :|.:|::||:.:.|.|..:..:::::.:||..|:.|.::|....
 Worm   177 E-------HWWYYISYFIIISVIFDYLLPFVIMFIANMKVINELRKSRKERALLTTSLQKEQNTT 234

  Fly   341 TMLLCVVIVFFMLNFLPLVLNISEAFYSTIDHK-------ITKISNLLITINSSVNFLIYIIFGE 398
            .|||.|.|:|...:|..:.|.:.|:.:....::       :.::||:||.|:....|.||..|..
 Worm   235 VMLLVVTILFGFCHFFSMALKLFESIFKDFLNRHNEYFEVMIEVSNILIVIHIGTTFFIYYFFSA 299

  Fly   399 KFKRIFLLIFFKRRLSRDQPDLIHYESSISNNGDGTLNHR 438
            :|:.|...:|.||             |::.:|....||.|
 Worm   300 RFRNILCYLFKKR-------------SNLPDNSLTDLNKR 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	81/309 (26%)
		TM helix 1	115..141	CDD:410630	4/25 (16%)
		TM helix 2	147..172	CDD:410630	6/24 (25%)
		TM helix 3	193..223	CDD:410630	11/32 (34%)
		TM helix 4	235..255	CDD:410630	4/19 (21%)
		TM helix 5	289..314	CDD:410630	9/33 (27%)
		TM helix 6	334..362	CDD:410630	9/27 (33%)
		TM helix 7	372..397	CDD:410630	8/31 (26%)
frpr-6	NP_872220.1	7tmA_FMRFamide_R-like	9..305	CDD:410630	83/326 (25%)
		TM helix 1	9..35	CDD:410630	6/43 (14%)
		TM helix 2	41..67	CDD:410630	7/26 (27%)
		TM helix 3	90..120	CDD:410630	11/29 (38%)
		TM helix 4	132..152	CDD:410630	4/19 (21%)
		TM helix 5	183..208	CDD:410630	6/24 (25%)
		TM helix 6	228..258	CDD:410630	9/29 (31%)
		TM helix 7	273..298	CDD:410630	8/24 (33%)