Protein Alignment FMRFaR and frpr-14

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_493779.3
• Gene: frpr-14 / 187113
• WormBaseID: WBGene00019496
• Length: 349
• Species: Caenorhabditis elegans
• Alignment Length: 330
• Identity: 98/330 - (29%)
• Similarity: 159/330 - (48%)
• Gaps: 33/330 - (10%)

  Fly    84 EDLGLDPDPNWTRICEDVYNPLLENNRIEFWVCGVLINIVGVLGILGNIISMIILSRP-QMRSSI 147
            |.|..:|.|.:...|....:|  |.......|.|||:.|||::|::||::.:.....| |...|.
 Worm     7 ELLDFEPPPIFCNSCLGSTDP--EYLTYNLAVSGVLLAIVGMIGLIGNMLVVKTYLHPEQAIHST 69

  Fly   148 NYLLTGLARCDTVLIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTF 212
            :..|..||..|..|::|::.||.:.:   :..|.:....|:|...:|.|||:..:.||:|:|...
 Worm    70 SIYLAALAFSDFFLVLTAMFLFVLEA---WRHHDYPTLAYLYVIGAPIVFPVAAVFQTSSVYFCV 131

  Fly   213 TVTLERYVAVCHPLKARAL-CTYGRAKIYFIVCVCFSLAYNMPRFWEVLTV-TYPEPGKDVILHC 275
            ...::.::.|..|...:.| ||..||||..:|.:.....||:|.|:|:..| ...|.|:|.:..|
 Worm   132 AAAVDCFIMVVLPESVKQLYCTPRRAKITCVVLMLICFIYNIPHFFELEKVDCLDEDGRDSMQIC 196

  Fly   276 VRPSRLRRSETYINIYIHWCYLIVNYIIPFLTLAILN-CLIYRQVKRANRERQRLSRSEKREIGL 339
              |:.:|....|..||..:.|.....|.|...|.:|| |:::..|.:.       |.:|..|..
 Worm   197 --PTDIRLDPAYYAIYYTYMYTTFLAIGPLTLLILLNICVVFTVVTKG-------SSNENGEDD- 251

  Fly   340 ATMLLCVVIVFF--------MLNFLPLVLNISEAFYSTIDHKITKISNLLITINSSVNFLIYIIF 396
             |:.|.:|:.||        |:||:.::||........:|     :||||:.:|.:.||..|:||
 Worm   252 -TISLILVVFFFIFCNFTALMVNFMEIILNDPSMLVYFVD-----LSNLLVVVNGTANFFCYLIF 310

  Fly   397 GEKFK 401
            |..|:
 Worm   311 GTSFR 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	91/300 (30%)
		TM helix 1	115..141	CDD:410630	10/25 (40%)
		TM helix 2	147..172	CDD:410630	8/24 (33%)
		TM helix 3	193..223	CDD:410630	8/29 (28%)
		TM helix 4	235..255	CDD:410630	7/19 (37%)
		TM helix 5	289..314	CDD:410630	8/25 (32%)
		TM helix 6	334..362	CDD:410630	10/35 (29%)
		TM helix 7	372..397	CDD:410630	9/24 (38%)
frpr-14	NP_493779.3	7tmA_FMRFamide_R-like	36..318	CDD:410630	91/299 (30%)
		TM helix 1	36..62	CDD:410630	10/25 (40%)
		TM helix 2	69..94	CDD:410630	8/24 (33%)
		TM helix 3	112..142	CDD:410630	8/29 (28%)
		TM helix 4	155..175	CDD:410630	7/19 (37%)
		TM helix 5	208..233	CDD:410630	8/24 (33%)
		TM helix 6	249..276	CDD:410630	9/28 (32%)
		TM helix 7	286..311	CDD:410630	10/29 (34%)