Protein Alignment FMRFaR and C39B10.1

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_509754.1
• Gene: C39B10.1 / 183330
• WormBaseID: WBGene00008021
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 381
• Identity: 72/381 - (18%)
• Similarity: 150/381 - (39%)
• Gaps: 85/381 - (22%)

  Fly    59 NNSQPTLQIVLN-----HTEVQTDL------QYPHYEDLGLDPDPNWTRICEDVYNPLLENNRIE 112
            |.:.||:....|     ||....::      :|.||:.....            ||
 Worm     4 NTTWPTIDWCFNMEMWLHTMATQNISQQMRSKYAHYKTFSYR------------YN--------- 47

  Fly   113 FWVCGVLINIVGVLGILGN--IISMIILSRP-QMRSSINYLLTGLARCDTVLIITSILLFGIPSI 174
                |:|..::.:||:.|:  ::..|..||. ..|.:::  |..:...|.:.::..:..:.|||:
 Worm    48 ----GLLTLVLILLGLTGSSLLLKQIYGSRVFSKRLAVH--LGMICFWDIIYLLCCLSTYCIPSL 106

  Fly   175 YPYTGHFFGYYNYVYPFISP-AVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAK 238
            .......:|.::|:..|:.| |.|.:     :.:|:..|.:|||||:||..||:.|.     |..
 Worm   107 IYSVTPIYGPFSYILFFLQPFASFCV-----SCTIWQVFAITLERYLAVSSPLEQRT-----RKA 161

  Fly   239 IYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPS------RLRRSETYINIYIHWCYL 297
            .:.:..:|.::.     |...:....|.|.::.::.|...:      .:.|:.|.:..|......
 Worm   162 KFGVGWICVAIT-----FCAFILNLLPVPFENELVDCYEINFDSNGLPMFRNHTMMKPYYDDKIR 221

  Fly   298 IVNYIIPFL---------TLAILNCLIYRQVKRANRER-------QRLSRSEKREIGLATMLLCV 346
            |..:::.|.         .:.::..|..:.::..::..       .|.:|:....:.|......:
 Worm   222 IYRFLVHFFPDLLFRAPTPIIVIGTLTVKTIQACSQRSVGNFQIGMRFNRNMPLRLSLLNFKFIL 286

  Fly   347 VIVFFMLNFLPLVL----NISEAFYSTIDHK--ITKISNLLITINSSVNFLIYIIF 396
            ....:|.|.:.|.|    |:....|....:.  :|..||:|:.::|:.|:|::..|
 Worm   287 CNTLYMFNTILLELLEYGNMENGDYDGYINSFYLTDASNMLLVVHSATNWLLFYKF 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	61/315 (19%)
		TM helix 1	115..141	CDD:410630	7/27 (26%)
		TM helix 2	147..172	CDD:410630	2/24 (8%)
		TM helix 3	193..223	CDD:410630	11/30 (37%)
		TM helix 4	235..255	CDD:410630	2/19 (11%)
		TM helix 5	289..314	CDD:410630	3/33 (9%)
		TM helix 6	334..362	CDD:410630	5/31 (16%)
		TM helix 7	372..397	CDD:410630	8/27 (30%)
C39B10.1	NP_509754.1	7tmA_FMRFamide_R-like	69..344	CDD:410630	56/291 (19%)
		TM helix 2	79..104	CDD:410630	2/26 (8%)
		TM helix 3	121..151	CDD:410630	12/34 (35%)
		TM helix 4	163..184	CDD:410630	2/25 (8%)
		TM helix 5	225..250	CDD:410630	2/24 (8%)
		TM helix 6	268..305	CDD:410630	7/36 (19%)
		TM helix 7	318..343	CDD:410630	8/25 (32%)