Protein Alignment FMRFaR and frpr-13

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_505299.1
• Gene: frpr-13 / 179268
• WormBaseID: WBGene00019448
• Length: 365
• Species: Caenorhabditis elegans
• Alignment Length: 397
• Identity: 82/397 - (20%)
• Similarity: 168/397 - (42%)
• Gaps: 95/397 - (23%)

  Fly    46 TEGPTVRY-DLFPQNNSQPTLQIVLNHTEVQTDLQYPHYEDLGLDPDPNWTRI---CEDVYNPLL 106
            |..|.:.: ||:  :...|..|   |.|......|:  ||:..:....|.|::   |...::..|
 Worm     2 TSEPDLHFQDLY--DKIDPPFQ---NATPFARTGQF--YENRSITDFNNTTQMIDQCPFKFSQHL 59

  Fly   107 ENNRIEFWVCGVLINIVGVLGILGNIISMIILSRP-QMRSSINYLLTGLARCDTVLIITSILLFG 170
            ....|..::.|:::.        |  ||:.:.:|| |:::::.:||..|:..:.:.::.|..:|.
 Worm    60 ALATIPLFIVGLILT--------G--ISIYVYTRPYQLKTTVGFLLAWLSVFEWLFLLASFQVFS 114

  Fly   171 IPSI-----------YPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCH 224
            |...           ||.    ...|:.:|      :||:....:...:.::..:::::::||..
 Worm   115 ISETAFFACPTTENEYPK----IKAYSEIY------IFPLTHATKYMCVCISIIISIQQWIAVFL 169

  Fly   225 PLKARALCTYGRAKIYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVR--PSRLRRSETY 287
            |::|:.||...|.|.:.:..:..|...::|:|:        |.|    :|.:.  |.:....|.|
 Worm   170 PMEAKDLCNMERTKRFLVGSLVISSILSLPKFF--------EKG----IHEINGWPWQTNAVEKY 222

  Fly   288 INIYIHWCYLIVNYIIP--------FLTLAILNCLIYRQVKRANRERQRLSRSEKREIGLATMLL 344
            ..:      .:|.|:..        |..|.|:|..|...:|.::.||.|::....|:...:.|||
 Worm   223 TFL------KVVQYVEENVFSVFKIFFLLFIINVSIILLLKYSHNERIRMTSQSIRDPRTSIMLL 281

  Fly   345 CVVIVF-------FML-------NFLPLVLNISEAFYSTIDHKITKISNLLITINSSVNFLIYII 395
            .|:..:       |:|       ::||     |:.:.:..|     :||..:..:...:|..|:|
 Worm   282 AVLFAYVVTHLPRFLLQYDGHWKHYLP-----SDMYIARND-----LSNYFMCCHPLFSFADYLI 336

  Fly   396 FGEKFKR 402
            |.||:::
 Worm   337 FSEKYRK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	66/325 (20%)
		TM helix 1	115..141	CDD:410630	4/25 (16%)
		TM helix 2	147..172	CDD:410630	5/24 (21%)
		TM helix 3	193..223	CDD:410630	3/29 (10%)
		TM helix 4	235..255	CDD:410630	3/19 (16%)
		TM helix 5	289..314	CDD:410630	6/32 (19%)
		TM helix 6	334..362	CDD:410630	9/41 (22%)
		TM helix 7	372..397	CDD:410630	5/24 (21%)
frpr-13	NP_505299.1	7tmA_FMRFamide_R-like	61..345	CDD:410630	67/331 (20%)
		TM helix 1	61..84	CDD:410630	5/32 (16%)
		TM helix 2	91..116	CDD:410630	5/24 (21%)
		TM helix 3	138..168	CDD:410630	4/35 (11%)
		TM helix 4	180..200	CDD:410630	3/19 (16%)
		TM helix 5	226..251	CDD:410630	6/24 (25%)
		TM helix 6	271..301	CDD:410630	7/29 (24%)
		TM helix 7	313..338	CDD:410630	6/29 (21%)