Protein Alignment AhcyL1 and AHCY

DIOPT Version :10

• Sequence 1: NP_647746.1
• Gene: AhcyL1 / 38342
• FlyBaseID: FBgn0035371
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001309015.1
• Gene: AHCY / 191
• HGNCID: 343
• Length: 434
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 220/427 - (51%)
• Similarity: 307/427 - (71%)
• Gaps: 3/427 - (0%)

  Fly    96 CVRNIGAQHAFGRREIEIAEQEMPGIIALKKRAAEDKPLKDAKIVGCTHINAQTAVLIETLVELG 160
            |..:||.. |:||:.::|||.||||::.:::|.:..||||.|:|.||.|:..:|||||||||.||
Human    10 CEADIGLA-AWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLG 73

  Fly   161 ASVRWAACNIYSTQNEVAAALAESGIPIFAWRGETEEDFWWCIDRCVNAENWQPNMILDDGGDAT 225
            |.|:|::|||:|||:..|||:|::|||::||:|||:|::.|||::.:..::...|||||||||.|
Human    74 AEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLT 138

  Fly   226 HLMLKKYPTMFKLVKGIVEESVTGVHRLYQLSKAGKLTVPAMNVNDSVTKTKFDNLYSCKESILD 290
            :|:..|||.:...::||.||:.||||.||::...|.|.|||:||||||||:||||||.|:||::|
Human   139 NLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLID 203

  Fly   291 SLKRSTDVMFGGKQVVVCGYGDVGKGCAQALKGQGCIVYITEIDPICALQASMDGFRVVKLNEVI 355
            .:||:||||..||..||.|||||||||||||:|.|..|.|||||||.||||:|:|:.|..::|..
Human   204 GIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEAC 268

  Fly   356 RNVDIVVTATGNKNVVVREHMDKMKSGCIVCNMGHSNTEIDVNGLRTPDLTWEKVRSQVDHIIWP 420
            :..:|.||.||..::::..|.::||...||||:||.:.||||..|....:....::.|||.....
Human   269 QEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLK 333

  Fly   421 EGKYIILLAEGRLVNLSCS-SIPSFAVSITSATQALALIELFNAPPGRYKSDVYLLPKKMDEYVA 484
            .|:.||||||||||||.|: ..|||.:|.:...|.:|.|||: ..|.:|...|:.||||:||.||
Human   334 NGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELW-THPDKYPVGVHFLPKKLDEAVA 397

  Fly   485 SLHLPTFDAHLTELSDEQAKYMGLNKAGPFKPNYYRY 521
            ..||...:..||:|:::||:|:|::..|||||::|||
Human   398 EAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AhcyL1	NP_647746.1	AdoHcyase	96..520	CDD:214963	217/424 (51%)
AHCY	NP_001309015.1	AdoHcyase	10..433	CDD:214963	217/424 (51%)