Protein Alignment Mrtf and Myocd

DIOPT Version :10

• Sequence 1: NP_001137879.3
• Gene: Mrtf / 38338
• FlyBaseID: FBgn0052296
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: NP_001401161.1
• Gene: Myocd / 246297
• RGDID: 631347
• Length: 986
• Species: Rattus norvegicus
• Alignment Length: 1330
• Identity: 278/1330 - (20%)
• Similarity: 445/1330 - (33%)
• Gaps: 497/1330 - (37%)

  Fly   340 KNKESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRPNREDLER 404
            |.:..|:::|..||...||..||:||.||:....|:..|:|:.|||.|.|:.|::.|.:|..|..
  Rat    15 KFRSVLQLRLQQRRTQEQLANQGLIPPLKSPTEFHDPRKKLDSAKTEDSLRRKVRNRSDRASLVN 79

  Fly   405 LHILEEDECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEKIVKEGLV 469
            :|||:....  :.|:...|..||:|||||.||.:|..|||||||::||||..:..:::.:|...|
  Rat    80 MHILQASTA--ERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEV 142

  Fly   470 SFKATSEGLLTRPQHPHSYVTFDDDSLS---SESDTRQTPPRLDEAMVATSSSPTDVLQAAAASA 531
            |....::..           .|:|||..   |....|...|:      .:..|..|:....|
  Rat   143 SLSKAADAF-----------AFEDDSSRDGLSPDQARSEDPQ------GSGGSTPDIKSTEA--- 187

  Fly   532 GIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVKQETANLYE 596
                     |.||.|
  Rat   188 ---------PLAGPL-------------------------------------------------- 193

  Fly   597 ELCQSVTGTTASPVNHLYSPCSLASST--STLSPLSSIASPPPPPMTTTRLHLAPVSVKSDAPGK 659
            :..|.:|..:.|..|...|..|..|.:  ..|.|||:     |.|:.|        :|||.:.|.
  Rat   194 DTIQDLTPGSESDKNDTASQLSNQSDSGKQVLGPLST-----PIPVHT--------AVKSKSLGD 245

  Fly   660 DKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQPEETSYQLMLEQQNCLLKFLENLNKNQ 724
            .|||.|....|..|.:.:|:|:|. ||....:|  ...|.:::|..:|:||...|: |:.|::.|
  Rat   246 SKNRHKKPKDPKPKVKKLKYHQYI-PPDQKAEK--SPPPMDSAYARLLQQQQLFLQ-LQILSQQQ 306

  Fly   725 SIIPAPSAPGVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPISLPNTISITSSSGGAPLNFG 789
            .
  Rat   307 Q---------------------------------------------------------------- 307

  Fly   790 DATMLTPTPAATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHPPPLPSPALSV-----SSSI 849
                                 ...|||.|..||.||.....|..|...|..|...:     |||.
  Rat   308 ---------------------QQQQQQQQQQQQQQQQRFSYPGMHQAHLKEPNEQMTRNPNSSST 351

  Fly   850 P----PSPATSYAESTTSSITDL------ARLEKMKVSDLKQHLKRRNLPVSGPKPHLIERLKPY 904
            |    |......:.|..:.::.|      ..|:.:|||:|:|.|:.|.|||||.|..|::||:|:
  Rat   352 PLNNTPLSPVKNSLSGQTGVSSLKPGPLPPNLDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPF 416

  Fly   905 LPLEPLDSNVTPAPTSNNSNT-----TPEVITISDAMDTS--NCGLLEQPPPVTMLVSDASMEHE 962
                 .|....|.|...:..|     ||..:....:..:.  :.|.....||::...||.|....
  Rat   417 -----QDCAGNPVPNFGDITTVTFPVTPNTLPSYQSSPSGFYHFGSTSSSPPISPASSDLSAAGS 476

  Fly   963 QMDVVQQQMD----NTHPM---TLQTIL--------PPQPQTATIILTNEELLREQQRKIDELQR 1012
            ..|.......    :..|:   |.:::|        |.:|.  .:....:::|.|:|:.|::|..
  Rat   477 LPDTFTDASPGFGLHASPVPACTDESLLSSLNGGSGPSEPD--GLDSEKDKMLVEKQKVINQLTW 539

  Fly  1013 QLQRSQQELQKIRQRQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQVEKNF 1077
            :|::.|::::::|.:.|:|:.           .....:.:..:.||..  |:.::..|      |
  Rat   540 KLRQEQRQVEELRMQLQKQKS-----------GCNDQKPLPFLATTIK--QEDVSSCP------F 585

  Fly  1078 PAKVTVKATGGNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQK 1142
            .|:   :|:|....|                          ||.:|||
  Rat   586 AAQ---QASGKGQGH--------------------------SSDSPPP----------------- 604

  Fly  1143 QKAAAAAAAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLLTQKTQTVFIPFNNNNHINNAS 1207
                |...||......:...|.....:.....|...|...:..| :..|.:.:|.:.|||...||
  Rat   605 ----ACETAQLLPHCVESSGQTHVLSSTFLSPQCSPQHSPLGTL-KSPQHISLPPSPNNHYFLAS 664

  Fly  1208 AKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQ 1272
            :....::::                        ..:||    :::.|...|.|
  Rat   665 SSGAQRENH------------------------GVSSP----NSSQGCAQNSG------------ 689

  Fly  1273 HMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPIETKSIITQQ 1337
               ||             ...||:.:|.::|...|    .:|.|..:|..|.:.|. .||.:...
  Rat   690 ---AH-------------EGHPPSFSPPSSSLHQP----FSGTQADSSHSSGLNPC-PKSPVIHP 733

  Fly  1338 QLQQLQQQQQQQQQFQ------PVQQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAAALNGL 1396
            ::..||...:....|.      |...|...::.|         ||.||:|.||
  Rat   734 KMTGLQSSDKVGPTFSIPSPTFPKSSPTVPEITQ---------PPSYEDAVKQ------------ 777

  Fly  1397 LPLVKIKEEPVQSPAPSAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPESA-----ALE 1456
                                            ...:|:|:.::||:||:.||:|..|     .|:
  Rat   778 --------------------------------QMTRSQQMDELLDVLIESGEMPADAREDHSCLQ 810

  Fly  1457 PI--------TPLTPLPELSMFNGATPTTAAGGASI------------VPLVPKLETPVTPVQNL 1501
            .|        :|.|.||:.|    |:...|:.|..|            :.::....:|:..|.::
  Rat   811 KIPKIPGSSCSPTTILPKSS----ASFEQASSGGQISFDHYATDSEEHLEVLLNSHSPIGKVSDV 871

  Fly  1502 ------------DVAMDTNVQHVGFASNQA---------------PNHVFIESIDMASPLQTDSS 1539
                        |..||      ||....|               |.|.      ..||...|||
  Rat   872 TLLKIGSEEPPFDGIMD------GFPGKAAEDLFSAHELLPGPLSPMHT------QLSPPSVDSS 924

  Fly  1540 AID---AESVAKTLDIFLEQHHATPPPSTP 1566
            .:.   .||..:|:: :|:   .|||.|||
  Rat   925 GLQLSFTESPWETME-WLD---LTPPSSTP 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrtf	NP_001137879.3	RPEL	387..412	CDD:128947	9/24 (38%)
		RPEL	433..458	CDD:128947	15/24 (63%)
		SAP	871..905	CDD:460424	18/33 (55%)
Myocd	NP_001401161.1	RPEL	106..131	CDD:128947	15/24 (63%)
		SAP	383..416	CDD:460424	17/32 (53%)