Protein Alignment ProRS-m and Pars2

DIOPT Version :10

• Sequence 1: NP_647737.1
• Gene: ProRS-m / 38331
• FlyBaseID: FBgn0027082
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_001014086.2
• Gene: Pars2 / 313429
• RGDID: 1305345
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 440
• Identity: 188/440 - (42%)
• Similarity: 276/440 - (62%)
• Gaps: 21/440 - (4%)

  Fly     3 KASRIFCPALITPKNAVVKQTEQLS----------RSQKLLTELGLVKSGSNGTYQIMPMAQRSV 57
            :..|:....:..|:|  :::.:.||          :||:|:.::||:...|.|.|.:||...|:|
  Rat    41 RGQRLVVSRMFQPQN--LREDQVLSLEGRASDLTCKSQRLMLQVGLILPASPGCYHLMPYTVRAV 103

  Fly    58 DKCIDLVQSNMQQAGGQKITLPILTPTGLWKKTGRLDGDISEFYMVRDRSGKQFLMSPTHEEAVT 122
            :|.:.::...||..|||||.:|.|:|..||:.|||.|....|...::||.||::.:.||||||||
  Rat   104 EKLVRVIDQEMQAIGGQKINMPSLSPAELWRATGRWDLMGRELLRLKDRHGKEYCLGPTHEEAVT 168

  Fly   123 AMLATTSPISYRQLPLRLFQIGPKFRDELKTRFGLMRAKEFLMKDMYSFDVSEETAMETYTLVNA 187
            |::|:...:||:||||.|:|:..|||||.:.||||:|.:||.|||||:||.|.|.|.|||:||..
  Rat   169 ALVASQKKLSYKQLPLLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFDSSSEAAQETYSLVCD 233

  Fly   188 AYDRLFKQLEVPFVKVNAATGIMGGSVSHEYHYVSPVGEDNLLQCSSCGFAGNSEVVK-APASCP 251
            ||.|||.:|.:.::|..|..|.:||::|||:.....:|||.|:.|.||.|:.|:|:|. :...||
  Rat   234 AYCRLFDRLGLRWMKARADVGSIGGTMSHEFQLPVDIGEDRLVVCPSCHFSANTEIVDLSQKICP 298

  Fly   252 SCNSSDLKEVRGVEVAHTFLLGDKYSKPLGATFLNTTGKPQSLVMGCYGIGITRVIAAALEVLSS 316
            .| ...|.|.:|:||.|||.||.|||....|.|.|..|:.....|||||:|:||::|||:||||:
  Rat   299 DC-QGPLTETKGIEVGHTFYLGTKYSSIFNAHFTNAHGESLLAEMGCYGLGVTRILAAAIEVLST 362

  Fly   317 DHELRWPKLLAPYDVCLIGPKQGSKEQPEAEVIE---NELLLNVGEICGHQELLHDDRKELTIGK 378
            :..:|||.|||||.||:|.||:||||....|::|   :::...:.::.|  |:|.|||..||||.
  Rat   363 EDCIRWPSLLAPYQVCIIPPKKGSKEAAATEIVERLYDDVTEALPQLRG--EVLLDDRTHLTIGN 425

  Fly   379 RLLEAKRLGHPLTIVVGAKSARLDSPKLEVHT-SKGETYELDFSETLKLV 427
            ||.:|.:||:|. :::.:|.|..|....||.: :.||...|.....::|:
  Rat   426 RLKDANKLGYPF-VIIASKRALEDPAHFEVWSQNTGEVVFLTKEGVMELL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ProRS-m	NP_647737.1	ProRS_core_prok	24..313	CDD:238402	137/299 (46%)
		ProRS_anticodon_short	328..428	CDD:238438	38/104 (37%)
Pars2	NP_001014086.2	ProRS_core_prok	70..359	CDD:238402	135/289 (47%)
		ProRS_anticodon_short	374..475	CDD:238438	38/104 (37%)