Protein Alignment Pxn and CG4009

DIOPT Version :10

• Sequence 1: NP_523891.2
• Gene: Pxn / 38326
• FlyBaseID: FBgn0011828
• Length: 1527
• Species: Drosophila melanogaster
• Sequence 2: NP_650588.2
• Gene: CG4009 / 42054
• FlyBaseID: FBgn0038469
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 683
• Identity: 204/683 - (29%)
• Similarity: 309/683 - (45%)
• Gaps: 121/683 - (17%)

  Fly   716 ERTLVNIRKHVQEGDNLTMKSEEYEFRDLLSREHLH-LVAELSGCMEHRE--MP--NCTDMCFHS 775
            :|:..:||..|.:|   ::.:...||....:..::| ..||.|...:...  :|  ||.:...:.
  Fly    32 KRSSFDIRPGVSDG---SLDALIKEFMPKYNGNNVHNSWAEPSASQQPLRCGVPPRNCLNDTRNL 93

  Fly   776 RYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVA 840
            .||::||:||||.:|.:|.:::.:|||.||                 ......|:|||:|.||..
  Fly    94 HYRTLDGSCNNLLYPEFGIAVSRYRRLLPP-----------------RQVEQAPNARLISLSLYG 141

  Fly   841 TKEITPDARI-THMVMQWGQFLDHDLDHAIPSVSSESWDGI--DCKKSC--EMAPPCYPIEVPPN 900
              |.|.:.|. |...||||||:.||       :|..|..|.  ||   |  ...|.|.||.:|..
  Fly   142 --EQTRNDRFRTMAAMQWGQFVAHD-------ISQLSTQGAPQDC---CAEPRHPRCLPINLPRG 194

  Fly   901 DPRV--RNRRCIDVVRS----SAICGSGMTSLFFDSVQ--HREQINQLTSYIDASQVYGYSTAFA 957
            .|..  ..:.|:...||    .|||         ..|:  ..|::...|:|:|.|.:||.:.:..
  Fly   195 GPIAYHTGKTCLHFARSVSDADAIC---------PKVEEPQPEKLTVATAYLDLSSIYGNNPSQN 250

  Fly   958 QELRNLTSQEGLLRV----GVHFPRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVG 1018
            :::|  ..:.|||:.    |.|:      ||.:..::| :|....:     |::..|||......
  Fly   251 RKVR--LFKGGLLKTSYTNGQHW------LPVSQNENG-ECGAKSE-----CYIVPDIRNRFSPT 301

  Fly  1019 LLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMG 1083
            :..:.|:.:|||||:|..|..||.....:.::||||||..||.|.||:..||||.:|.:...:.|
  Fly   302 IALLQTLLVREHNRLAENLALINPDHSDERIFQEARKINIAQFQKITYYDWLPLFVGRTYTYLNG 366

  Fly  1084 --------EY-QGYNPQLNPSIANEFATAALRFGHT-------IINPILHRLNET-----FQPIP 1127
                    || ..|:..:||:...||:.||.|:.||       ::.| ..|.|.|     |....
  Fly   367 LIYPVEPTEYVNDYDETVNPAAYAEFSAAAFRYAHTQIPGWFSLVAP-NRRSNRTMRLSDFLDRT 430

  Fly  1128 QGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTEL----TEKLFQTAHAVALD 1188
            :...||..:          ...|.|:|| ||.... |..|.|::.|:    ..|.|:   ....|
  Fly   431 ETIRLLDTS----------DNFDALLRG-LATQLH-KRSDGNIDREIKHYFNRKEFE---EYGSD 480

  Fly  1189 LAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGI 1253
            |.:|:|||.||.|:..||..|:.|.|..|.|:.|.|.||...:| ..::.||..||:|::.:||.
  Fly   481 LKSIDIQRARDFGLASYNDVREFCGLRRAVDWADFAHEIPGEKI-SLLRRLYATPDDVELGVGGT 544

  Fly  1254 LEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYY--ENPGVFSPEQLTQIKQANFGRVLCDVGDNF 1316
            ||..|.....||...|::.:||...|.|||.::  ||.|.||..||.:|::.:...:.|...:..
  Fly   545 LEYHVPDALFGPTLLCVIGKQFLNTRRGDRFFFERENEGGFSRAQLAEIRKVSLSSLFCSNANYL 609

  Fly  1317 DQVTENVFILAKHQGGYKKCEDIIGINLYLWQE 1349
            ..:..|||:..........|..|..|:|..||:
  Fly   610 HLIQPNVFVFPNSHNLLLNCNFIPQIDLSKWQD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxn	NP_523891.2	leucine-rich repeat	54..77	CDD:275380
		LRR	<55..>184	CDD:443914
		leucine-rich repeat	78..101	CDD:275380
		leucine-rich repeat	102..125	CDD:275380
		leucine-rich repeat	126..149	CDD:275380
		leucine-rich repeat	150..173	CDD:275380
		Ig_3	235..311	CDD:464046
		Ig	366..450	CDD:472250
		Ig strand B	384..388	CDD:409544
		Ig strand C	397..401	CDD:409544
		Ig strand E	420..424	CDD:409544
		Ig strand F	434..439	CDD:409544
		Ig strand G	447..450	CDD:409544
		Ig_3	458..533	CDD:464046
		Ig	553..644	CDD:472250
		Ig strand B	570..574	CDD:409353
		Ig strand C	584..588	CDD:409353
		Ig strand E	610..614	CDD:409353
		Ig strand F	624..629	CDD:409353
		Ig strand G	638..641	CDD:409353
		peroxidasin_like	898..1338	CDD:188658	141/478 (29%)
		VWC	1465..1523	CDD:278520
CG4009	NP_650588.2	An_peroxidase	95..617	CDD:460804	182/590 (31%)