Protein Alignment Pxn and bli-3

DIOPT Version :10

• Sequence 1: NP_523891.2
• Gene: Pxn / 38326
• FlyBaseID: FBgn0011828
• Length: 1527
• Species: Drosophila melanogaster
• Sequence 2: NP_490686.3
• Gene: bli-3 / 171608
• WormBaseID: WBGene00000253
• Length: 1497
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 166/561 - (29%)
• Similarity: 277/561 - (49%)
• Gaps: 92/561 - (16%)

  Fly   774 HSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYS-GHAKPSARLVSTS 837
            :..::..||..|||.:..||::.:...|.|...|.:|           :|| .::.||||.:|..
 Worm    25 NEEFQRYDGWYNNLANSEWGSAGSRLHRDARSYYSDG-----------VYSVNNSLPSARELSDI 78

  Fly   838 LVATKEITPDAR-ITHMVMQWGQFLDHDLDHAIPSVSSESWDGIDCKKSCEMAPPCYPIEVPPND 901
            |...:...|:.| .|.::..:.|.:.:::..:         :|:.|...      ...|:||..|
 Worm    79 LFKGESGIPNTRGCTTLLAFFSQVVAYEIMQS---------NGVSCPLE------TLKIQVPLCD 128

  Fly   902 PRVRNRRC-----IDVVRS--SAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQE 959
             .|.::.|     |...|:  ....|:|:.|       .|||||:.||:||.|.:||.:..:...
 Worm   129 -NVFDKECEGKTEIPFTRAKYDKATGNGLNS-------PREQINERTSWIDGSFIYGTTQPWVSS 185

  Fly   960 LRNLTSQEGLLRVGV--HFPRQKDMLPF---AAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGL 1019
            ||:.  ::|.|..||  :.|.....:|.   |.||    ..|.:..:.:  |:.||.||||..||
 Worm   186 LRSF--KQGRLAEGVPGYPPLNNPHIPLNNPAPPQ----VHRLMSPDRL--FMLGDSRVNENPGL 242

  Fly  1020 LAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGE 1084
            |:...|..|.||..|:::.:.:..|..:.::|.||::|.|.||.|....::|.::||.  ..:..
 Worm   243 LSFGLILFRWHNYNANQIHREHPDWTDEQIFQAARRLVIASMQKIIAYDFVPGLLGED--VRLSN 305

  Fly  1085 YQGYNPQLNPSIANEFATAALRFGHTIINPIL---HRLNE-TFQPIPQGH--LLLHKAFFAPWRL 1143
            |..|.|.:.|.|::.|..||.||.|:|:.|.:   .|.|: .|:....|:  |.|.:.::....:
 Worm   306 YTKYMPHVPPGISHAFGAAAFRFPHSIVPPAMLLRKRGNKCEFRTEVGGYPALRLCQNWWNAQDI 370

  Fly  1144 AYEGGVDPLMRGFLAVPAKLKTPDQNLNTE-LTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNV 1207
            ..|..||.::   |.:.:::...|.|:..| |.:.:|...|...||:.|.:|.||||:|:|.||.
 Worm   371 VKEYSVDEII---LGMASQIAERDDNIVVEDLRDYIFGPMHFSRLDVVASSIMRGRDNGVPPYNE 432

  Fly  1208 YRKLCNL------TVAQDFEDLAGEISSAEIRQKMKELYGHPDNV---DVWLGGILEDQVEGGKV 1263
            .|:...|      |:.:||.    :..:|:: :|:|||||  .|:   |.::||:|    |||:.
 Worm   433 LRRTFGLAPKTWETMNEDFY----KKHTAKV-EKLKELYG--GNILYLDAYVGGML----EGGEN 486

  Fly  1264 GP--LFQCLLVEQFRRLRDGDRLYYENP--GVFSPEQLTQI 1300
            ||  ||:.::.:||.|:|||||.::||.  |:|:.|::..|
 Worm   487 GPGELFKEIIKDQFTRIRDGDRFWFENKLNGLFTDEEVQMI 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxn	NP_523891.2	leucine-rich repeat	54..77	CDD:275380
		LRR	<55..>184	CDD:443914
		leucine-rich repeat	78..101	CDD:275380
		leucine-rich repeat	102..125	CDD:275380
		leucine-rich repeat	126..149	CDD:275380
		leucine-rich repeat	150..173	CDD:275380
		Ig_3	235..311	CDD:464046
		Ig	366..450	CDD:472250
		Ig strand B	384..388	CDD:409544
		Ig strand C	397..401	CDD:409544
		Ig strand E	420..424	CDD:409544
		Ig strand F	434..439	CDD:409544
		Ig strand G	447..450	CDD:409544
		Ig_3	458..533	CDD:464046
		Ig	553..644	CDD:472250
		Ig strand B	570..574	CDD:409353
		Ig strand C	584..588	CDD:409353
		Ig strand E	610..614	CDD:409353
		Ig strand F	624..629	CDD:409353
		Ig strand G	638..641	CDD:409353
		peroxidasin_like	898..1338	CDD:188658	139/435 (32%)
		VWC	1465..1523	CDD:278520
bli-3	NP_490686.3	dual_peroxidase_like	31..586	CDD:188652	166/555 (30%)
		PTZ00183	<803..923	CDD:185503
		COG4097	988..1415	CDD:443273
		NOX_Duox_like_FAD_NADP	1218..1402	CDD:99783