Protein Alignment Pxn and LOC1272535

DIOPT Version :10

• Sequence 1: NP_523891.2
• Gene: Pxn / 38326
• FlyBaseID: FBgn0011828
• Length: 1527
• Species: Drosophila melanogaster
• Sequence 2: XP_061513779.1
• Gene: LOC1272535 / 1272535
• VectorBaseID: AGAMI1_014216
• Length: 691
• Species: Anopheles gambiae
• Alignment Length: 691
• Identity: 232/691 - (33%)
• Similarity: 330/691 - (47%)
• Gaps: 80/691 - (11%)

  Fly   701 PTGEARQLARAAEIYERTLVNIRKHVQEGDNLTMKSEEYEFRDLLSREHLHLVAELSGCMEHREM 765
            |..:.|.|.:|:.:|...     .||...::.:..:..: :..|:|:.. :.|..||......:.
Mosquito    33 PAAQPRLLQKASHVYAPA-----AHVVTANHYSHAAAPH-YAPLVSKTR-YTVPFLSALQAQPQC 90

  Fly   766 PNCTDMCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPS 830
            | ....|..||||::||:|||||:||||.....:.||..|.|.:|.|:|.     :..:|...|:
Mosquito    91 P-APPACEKSRYRTLDGSCNNLQNPTWGTPNRRYGRLLTPKYGDGISLPT-----VSVTGQELPN 149

  Fly   831 ARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHAIPSVSSESWDGIDCKK----SC----- 886
            ||:||......::| ||...|...|||||.:.||:        |....|...||    .|
Mosquito   150 ARVVSLVAFGEQDI-PDPEYTLANMQWGQIMTHDM--------SMQAGGTQSKKHPTRCCTDEGK 205

  Fly   887 ----EMAP-PCYPIEVPPNDP--RVRNRRCIDVVRS----SAICGSGMTSLFFDSVQHREQINQL 940
                |.|| .||||.||.:||  ......||:.||:    ...|.....|      |..||:..:
Mosquito   206 LIGKERAPSSCYPIIVPEHDPAHSQTETECINFVRTLTDREDQCTPTHPS------QPAEQLTTV 264

  Fly   941 TSYIDASQVYGYSTAFAQELRNLTSQEGLLRV----GVHFPRQKDMLPFAAPQDGMDCRRNLDEN 1001
            |||:|.|.|||.|......:|..|.  |.:.|    |..:|...       |....:|.....:.
Mosquito   265 TSYLDLSLVYGNSDQQNAGIRAFTG--GRMAVVERDGYEWPPNN-------PNATTECENESRDE 320

  Fly  1002 TMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITF 1066
            .  |:::||.|||:..||..|..:.:|||||||.:|::.|.|||.:.|:||||:|..||.|||.:
Mosquito   321 V--CYLAGDSRVNQNPGLTIMQIVLLREHNRIADQLQKYNPHWDDELLFQEARRINIAQYQHINY 383

  Fly  1067 KQWLPLIIGESGMEMM--------GEY-QGYNPQLNPSIANEFATAALRFGHTIINPILHRLNET 1122
            .:|||:.:|...|...        ||| ..|:|..:||:.|..||||.|:.|:.|...|..::|.
Mosquito   384 YEWLPIFLGWENMVKNRLIYRVKGGEYINDYDPSQDPSVLNSHATAAFRYFHSQIEGRLDLVSEI 448

  Fly  1123 FQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVAL 1187
            .:  |.|.|.|...|..|..:......|.|.||....|.:|  .|.|.:.|:...||:.......
Mosquito   449 RK--PTGSLRLSDWFNRPSIIEAGDNYDFLTRGLATQPEEL--TDTNFDAEIKHFLFRRGRPFGG 509

  Fly  1188 DLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGG 1252
            ||.||:|||.||||:.|||.||:.|....|..:|||...||..:: .|::.||...|::|:.:||
Mosquito   510 DLRAIDIQRNRDHGLAGYNDYREFCGFKRASTWEDLMDLISPQDV-SKLQSLYASIDDIDLTVGG 573

  Fly  1253 ILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPG---VFSPEQLTQIKQANFGRVLCDVGD 1314
            .||..|.|...||.|.|:|.|||.|.|..||.:||...   .|:.|||.::::|:..|:.||.|:
Mosquito   574 SLEAHVNGALAGPTFLCILTEQFYRTRVADRFFYERGDKDLAFTREQLAELRKASMARLFCDNGN 638

  Fly  1315 NFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNS 1355
            :...:....|:...|......|..|..::|.||::....||
Mosquito   639 HVASMQPKAFLRISHSNQVVPCSQIPEVDLSLWKDLSYDNS 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxn	NP_523891.2	leucine-rich repeat	54..77	CDD:275380
		LRR	<55..>184	CDD:443914
		leucine-rich repeat	78..101	CDD:275380
		leucine-rich repeat	102..125	CDD:275380
		leucine-rich repeat	126..149	CDD:275380
		leucine-rich repeat	150..173	CDD:275380
		Ig_3	235..311	CDD:464046
		Ig	366..450	CDD:472250
		Ig strand B	384..388	CDD:409544
		Ig strand C	397..401	CDD:409544
		Ig strand E	420..424	CDD:409544
		Ig strand F	434..439	CDD:409544
		Ig strand G	447..450	CDD:409544
		Ig_3	458..533	CDD:464046
		Ig	553..644	CDD:472250
		Ig strand B	570..574	CDD:409353
		Ig strand C	584..588	CDD:409353
		Ig strand E	610..614	CDD:409353
		Ig strand F	624..629	CDD:409353
		Ig strand G	638..641	CDD:409353
		peroxidasin_like	898..1338	CDD:188658	160/461 (35%)
		VWC	1465..1523	CDD:278520
LOC1272535	XP_061513779.1	None