Protein Alignment Pxn and mpo

DIOPT Version :10

• Sequence 1: NP_523891.2
• Gene: Pxn / 38326
• FlyBaseID: FBgn0011828
• Length: 1527
• Species: Drosophila melanogaster
• Sequence 2: XP_002935236.4
• Gene: mpo / 100490938
• XenbaseID: XB-GENE-482502
• Length: 725
• Species: Xenopus tropicalis
• Alignment Length: 704
• Identity: 281/704 - (39%)
• Similarity: 407/704 - (57%)
• Gaps: 51/704 - (7%)

  Fly   663 EAAKEIDLAINNTLDMLFSNRSDK-APPNYGELLRVFRFPTGEARQLARAAEIYERTLVNIRKHV 726
            ||.|.:|.|...|.|:|.:....| ..|:  :::..|:.|...:|...|||:....||..:.:.:
 Frog    42 EAKKLVDTAYKRTRDVLKARLKQKNVRPS--DVMAFFKQPVATSRTHIRAADYMGTTLELLSEKI 104

  Fly   727 QEGDNLTMKSEEYEFRDLLSREHLHLVAELSGC-MEHREMPNCTDMCFHSRYRSIDGTCNNLQHP 790
            |     ::....:...|:|:...|..:.::||| ..|...|     |.:||||:..|.|||.:.|
 Frog   105 Q-----SVYRRPFNITDVLTANQLDTIYKVSGCAFLHLSRP-----CPNSRYRTFTGECNNRRFP 159

  Fly   791 TWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLV--ATKEITPDARITHM 853
            .:|.|...:.||.|..||:..|:|.|||:....:|...|.||.||..::  ..:|.|.|.:.:.|
 Frog   160 NFGVSNRPYTRLLPAQYEDSRSLPRGWTENRRINGFMLPLARAVSNQILQFPEREQTLDNQRSLM 224

  Fly   854 VMQWGQFLDHDLDHAIPSVSSESW-DGIDCKKSCEMAPPCYPIEVPPNDPRVRNRR-CIDVVRSS 916
            .|||||::|||:|.|..:.:..|: .||||..||....||:|:.:||||||::||. ||.:.|||
 Frog   225 FMQWGQWIDHDVDLAPETPARSSFLKGIDCDHSCAKELPCFPLRIPPNDPRIQNRSDCIPLFRSS 289

  Fly   917 AICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTS-QEGLLRVGVHF---- 976
            ..|..|..         .||||.||||:|||||||.:...|:.|||.|: |.||:.|...|
 Frog   290 PACVPGPV---------LEQINVLTSYVDASQVYGSTNDLARMLRNNTAGQLGLMAVNTRFTDGG 345

  Fly   977 -PRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQI 1040
             |    .|||:..::.. |....:.:.:.||::||.||:||.||.|.|||::|||||||.:|::|
 Frog   346 LP----YLPFSTMKEDF-CVLTNETSGLPCFLAGDARVSEQPGLTAFHTIFVREHNRIARELRRI 405

  Fly  1041 NSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAAL 1105
            |.:|.|:.::|||||||||..|.|.:|.:|||::|.|...::..|..||..:||..:|.| :...
 Frog   406 NPNWTGEIIFQEARKIVGAVEQKINYKDYLPLLLGSSMPRVLPRYTTYNDSVNPGASNVF-SLVF 469

  Fly  1106 RFGHTIINPILHRL------NETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLK 1164
            |.|||:|.|.:.||      :.:..|:|     ||..||..||:..|||||||:||.:|..|||.
 Frog   470 RMGHTMIQPFIFRLVDGYRASSSLPPVP-----LHLTFFNTWRVILEGGVDPLLRGLIANKAKLN 529

  Fly  1165 TPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISS 1229
            |..|.|.|:||:.||:....:.|||.|||:|||||||:||||.:|:||.|:..::..:||..:.:
 Frog   530 TQTQILVTQLTDHLFELFKRLGLDLGAINMQRGRDHGLPGYNAFRRLCGLSQPRNESELAAVLRN 594

  Fly  1230 AEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSP 1294
            .::.||:..|||.|||:|:|:|.:.|..:..|:||.|..||:.:||||.|||||.|||...||:|
 Frog   595 NQLAQKLISLYGTPDNIDIWMGAVAEPLITNGRVGELLACLIGDQFRRTRDGDRFYYERASVFTP 659

  Fly  1295 EQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQ 1348
            .||..|::|:..|::|| .....:|..:||....:...:.:|..|..::|..|:
 Frog   660 AQLRSIERASLARIVCD-NTRITEVPRDVFKANNYPANFVRCSSIPALDLSPWR 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxn	NP_523891.2	leucine-rich repeat	54..77	CDD:275380
		LRR	<55..>184	CDD:443914
		leucine-rich repeat	78..101	CDD:275380
		leucine-rich repeat	102..125	CDD:275380
		leucine-rich repeat	126..149	CDD:275380
		leucine-rich repeat	150..173	CDD:275380
		Ig_3	235..311	CDD:464046
		Ig	366..450	CDD:472250
		Ig strand B	384..388	CDD:409544
		Ig strand C	397..401	CDD:409544
		Ig strand E	420..424	CDD:409544
		Ig strand F	434..439	CDD:409544
		Ig strand G	447..450	CDD:409544
		Ig_3	458..533	CDD:464046
		Ig	553..644	CDD:472250
		Ig strand B	570..574	CDD:409353
		Ig strand C	584..588	CDD:409353
		Ig strand E	610..614	CDD:409353
		Ig strand F	624..629	CDD:409353
		Ig strand G	638..641	CDD:409353
		peroxidasin_like	898..1338	CDD:188658	199/452 (44%)
		VWC	1465..1523	CDD:278520
mpo	XP_002935236.4	An_peroxidase	146..688	CDD:460804	245/562 (44%)