DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1317 and MARCHF11

DIOPT Version :9

Sequence 1:	NP_001163328.1	Gene:	CG1317 / 38300	FlyBaseID:	FBgn0035333	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_001096032.1	Gene:	MARCHF11 / 441061	HGNCID:	33609	Length:	402	Species:	Homo sapiens

Alignment Length:	118	Identity:	34/118 - (28%)
Similarity:	56/118 - (47%)	Gaps:	10/118 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ICRVCRCEAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEYCELCSYSFSFQPIYAPDMPRV 73
            ||::|...|:... |..||.|.||::|.||.||:.|:.......||||.|.:.   :.|..|.:.
Human   169 ICKICFQGAEQGE-LLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYH---VIAIKMKQP 229

  Fly    74 LPIKDVLVGL-----MSAVLEGARCWLHYTLVGLAWFGVVPLSAYRTYRYLFR 121
            ...:.:.:.|     |.||:.|: .:|..::..|.|....|.:.::....||:
Human   230 CQWQSISITLVEKVQMIAVILGS-LFLIASVTWLLWSAFSPYAVWQRKDILFQ 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1317	NP_001163328.1	RINGv	9..56	CDD:128983	18/46 (39%)
CG1317	NP_001163328.1	DotA_TraY	<737..913	CDD:275142
MARCHF11	NP_001096032.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..161
		RINGv	169..215	CDD:128983	18/46 (39%)
		YXXL motif	371..374
		PDZ-binding	399..402
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810