DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1317 and Marchf4

DIOPT Version :9

Sequence 1:	NP_001163328.1	Gene:	CG1317 / 38300	FlyBaseID:	FBgn0035333	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_001038998.1	Gene:	Marchf4 / 381270	MGIID:	2683550	Length:	409	Species:	Mus musculus

Alignment Length:	274	Identity:	55/274 - (20%)
Similarity:	93/274 - (33%)	Gaps:	89/274 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDDLSQGDICRVCRCEAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEYCELCSYSFSFQPI 65
            :|...:..:||:| .:......|..||.|.||:|..||.||:.|:.......||||.|.:....|
Mouse   153 LDSGMRTPLCRIC-FQGPEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAI 216

  Fly    66 YAPDMPRVLPIKDVLVGL-------MSAVLEGARCWLHYTLVGLAWFGVVPLSAYRTYRYLFRAS 123
            ...:     |::...:.|       ::|.:.|:.    :.:..::|.      .:.|:....:..
Mouse   217 STKN-----PLQWQAISLTVIEKVQIAAAILGSL----FLIASISWL------IWSTFSPSAKWQ 266

  Fly   124 SFDMILTLPFDIFSVENLASDAFRGCFVVTCTLLSFIGLVWLREQILHGG-------------GP 175
            ..|::..:.:.::           |...|.|     |||      |:|.|             ..
Mouse   267 RQDLLFQICYGMY-----------GFMDVVC-----IGL------IIHEGPSVYRIFKRWQAVNQ 309

  Fly   176 DW--LERDDAP------------LQAAAANPAPDPAAEAAPQPQDDNNNADDNEAPAPADNDGQD 226
            .|  |..|...            ||.:::..|..|:||             :..|..||..:|..
Mouse   310 QWKVLNYDKTKDLEDQKSGGRTNLQTSSSAQANLPSAE-------------EEAASPPAREEGPT 361

  Fly   227 AQAQDAAPAAAAPV 240
            .    ||...:.||
Mouse   362 R----AASHPSGPV 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1317	NP_001163328.1	RINGv	9..56	CDD:128983	17/46 (37%)
CG1317	NP_001163328.1	DotA_TraY	<737..913	CDD:275142
Marchf4	NP_001038998.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	92..133
		RING_CH-C4HC3_MARCH4_9	161..211	CDD:319725	20/50 (40%)
		RING-CH finger (C4HC3-type)	162..207	CDD:319725	17/45 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	323..372		14/66 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..409
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810