DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1317 and marc-3

DIOPT Version :9

Sequence 1:	NP_001163328.1	Gene:	CG1317 / 38300	FlyBaseID:	FBgn0035333	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_492502.2	Gene:	marc-3 / 172767	WormBaseID:	WBGene00007643	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	61/310 - (19%)
Similarity:	89/310 - (28%)	Gaps:	137/310 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ICRVCRC--------EAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEYCELCSYSFSFQPI 65
            :||:|.|        ..|...||..||.|:|::...|:.||..|:..:....||:|.::|.
Worm    12 VCRICMCGETSIPYLGQQAGEPLISPCKCSGTMGLFHRSCLEHWLTLTSTTNCEICKFAFK---- 72

  Fly    66 YAPDMPRVLPIKDVLVGLMSAVLEGA--------RCWLHYTLVGL----AWFGVV-----PLSAY 113
                      ||......:..:.:|.        ..::.:..|.|    |:|||.     .|.|.
Worm    73 ----------IKQKSRNFIDYIRQGGYKKLQSNRNPFIDFAFVLLILPFAFFGVFMSVEGALYAG 127

  Fly   114 RTYRYLFRASSFDMILTLPFDIFSVENLASDAFRGCFVVTCTLLSFIGL---------------- 162
            |.|.|.|.....|....|     .|.|..|        :.|.|..|:.|
Worm   128 RKYHYAFENRDNDENGNL-----EVRNQTS--------LECALFLFVALLLFSAFITLVVSALWH 179

  Fly   163 ------VWL-------------REQILH--------GGG---------------------PDWLE 179
                  :|.             .||.:|        |||                     |:...
Worm   180 HFRQYKIWQAKNKIMFVVDQLDAEQSMHFNPQWKKQGGGWKEKIAKFWGEIRRRPTRAYIPEIAR 244

  Fly   180 RDDAPLQAAAANPAPDPAAEAAP---------QPQDDNNNADD---NEAP 217
            .|..|:         :|....:|         .|..:|.:..|   ||.|
Worm   245 NDSIPI---------EPVVGISPVLVANFNRTSPDSNNTHHHDESRNEIP 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1317	NP_001163328.1	RINGv	9..56	CDD:128983	17/54 (31%)
CG1317	NP_001163328.1	DotA_TraY	<737..913	CDD:275142
marc-3	NP_492502.2	RING_Ubox	12..71	CDD:388418	18/58 (31%)
marc-3	NP_492502.2	RING-CH finger (C4HC3-type)	13..67	CDD:319361	17/53 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900