DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1317 and marc-4

DIOPT Version :9

Sequence 1:	NP_001163328.1	Gene:	CG1317 / 38300	FlyBaseID:	FBgn0035333	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_001348646.1	Gene:	marc-4 / 171616	WormBaseID:	WBGene00016903	Length:	317	Species:	Caenorhabditis elegans

Alignment Length:	197	Identity:	42/197 - (21%)
Similarity:	77/197 - (39%)	Gaps:	54/197 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SQGDICRVCRCEAQP-DRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEY-----CELCSYS---- 59
            :..::||:|...... ..||..||.|:|::.::|:.|::.|:..|.::.     ||||.|.
Worm    75 ASANMCRICHTSTSTRSNPLISPCRCSGTLLFVHKACVVRWLEMSTRKMVPSPRCELCGYDYRRG 139

  Fly    60 --FSFQPIYAPDMPR------VLPIKDVLVGLM-----------SAVLEGARCWLH-YTLVGLAW 104
              |..:.::.|.:.|      ||.:..||:.:.           :|:|: .|.:.| .|.....|
Worm   140 NIFQMKSLHVPHVDRSSCLLNVLFLITVLIMIFCGYFTIQFIQENALLK-RRLFAHSSTNTAYTW 203

  Fly   105 ---------------------FGVVPLSAYRTYRYLFRASSFDMILTLPFDIFSVENLASDAFRG 148
                                 |...|:|:....:.:..||.|  :::....:|:.....|..||.
Worm   204 KRRGYFSGNGNGDGDGSSDGYFSRTPVSSLFDIKVVLCASMF--LVSFILALFTQYKAESTIFRC 266

  Fly   149 CF 150
            .|
Worm   267 IF 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1317	NP_001163328.1	RINGv	9..56	CDD:128983	15/52 (29%)
CG1317	NP_001163328.1	DotA_TraY	<737..913	CDD:275142
marc-4	NP_001348646.1	RING_CH-C4HC3_MARCH	80..133	CDD:319409	16/52 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810