DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1317 and MARCHF3

DIOPT Version :9

Sequence 1:	NP_001163328.1	Gene:	CG1317 / 38300	FlyBaseID:	FBgn0035333	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	XP_011541430.1	Gene:	MARCHF3 / 115123	HGNCID:	28728	Length:	305	Species:	Homo sapiens

Alignment Length:	274	Identity:	49/274 - (17%)
Similarity:	79/274 - (28%)	Gaps:	104/274 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 FVVTCTLLSFIGLVWLREQILHGGGPDWLERDDAPL-QAAAANP-----------APDPAAEAAP 202
            :::..|.|.|    |      :.|||...::....: ...||.|           ||.|......
Human    33 WIILATRLGF----W------NPGGPKRQQKSPQRMPPRTAARPERRSHRFRRRRAPKPPVGRQL 87

  Fly   203 QPQDDNNNADD--------------NEAPAPADNDGQDAQAQDAAPAAAAPVVDADADEQN--WN 251
            .|:...:...|              :...|...:|.|..|:...:||....:.....::..  |.
Human    88 CPRRAGSGGGDPRRRWKSCMNVEAISRVIAVCYHDNQPLQSPARSPARLHQLSCTRGEDGGGLWQ 152

  Fly   252 PMEWDRAAEELTWERLLGLDGSLVFLEHVFWIISLNTMFIFTFAFCPYCVGNF-------ILSSM 309
            |.||..|.                                        |..:|       :.||.
Human   153 PSEWAAAV----------------------------------------CHASFSQGRAAAVNSSA 177

  Fly   310 DLLQP----------EKPLLHFHGLITTLF--------GYCCIGLTLVVLHFFSRVFRLRRVCWF 356
            |...|          ||..| |..::..||        |:.|:...:..|||.||:..:..:...
Human   178 DSCHPEWLRNPGPQHEKRTL-FGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALT 241

  Fly   357 IGLCYIVVKVSLLS 370
            :.|..|.:..:|:|
Human   242 VALFTIYLFWTLVS 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG1317	NP_001163328.1	RINGv	9..56	CDD:128983
CG1317	NP_001163328.1	DotA_TraY	<737..913	CDD:275142
MARCHF3	XP_011541430.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900