DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1317 and hemk1

DIOPT Version :9

Sequence 1:	NP_001163328.1	Gene:	CG1317 / 38300	FlyBaseID:	FBgn0035333	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	XP_004914130.1	Gene:	hemk1 / 101732423	XenbaseID:	XB-GENE-854934	Length:	323	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	65/312 - (20%)
Similarity:	89/312 - (28%)	Gaps:	146/312 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 RILQVVCPDFLPYALSGDSAVNLQLLLLQIVLPGFFEQTQTRIWLKG-------LLRIWCTAVAW 548
            |:||.|.|.:||..                             ||.|       |:|.|
Frog    10 RLLQSVSPTWLPCR-----------------------------WLGGGEMSPSKLVRHW------ 39

  Fly   549 LLGIRSYLLPAPEPEPEIPAAGEEGVENAAGENENQEGEAADAAAQPPAPPPPPPPPVEPAPAPR 613
                :|.......|||:                |:.|...|.|......|..||
Frog    40 ----QSIFHDHGVPEPQ----------------ESSEILIAHALGSKTFPSLPP----------- 73

  Fly   614 NLAAAHQAIMQRDAPVGFQPYDKPSLFALRLCALLALMCLSIV-----------CAAMLTLTVPV 667
              :.||.::               |:..||....:|...|..|           ....|.:..||
Frog    74 --SVAHTSV---------------SVAQLRHIESMAQQRLKRVPIQYVIGEWDFLDITLQMRPPV 121

  Fly   668 YIGRRLMLIWSSQPDEKAAGAAAAEGAGEVVENLDPIDPEGARKNERLLRSHELYTAELGGYLCW 732
            :|.|         |:.:       |..|.|:         ||  :.||..|.|....|:|
Frog   122 FIPR---------PETE-------ELVGLVL---------GA--SRRLQCSAEPLVLEVG----- 154

  Fly   733 IVCRVVAAVVTL---LPQGRAAIVDKIK--------HWVRVALQYALPVLTL 773
              |...|..::|   |||.|...:||.|        :.|.:.||..:.||.|
Frog   155 --CGSGAVSLSLLQRLPQARITAIDKTKAAVKLTEDNAVSLGLQNQIQVLLL 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1317	NP_001163328.1	RINGv	9..56	CDD:128983
CG1317	NP_001163328.1	DotA_TraY	<737..913	CDD:275142	15/48 (31%)
hemk1	XP_004914130.1	PRK09328	50..322	CDD:236467	50/233 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900