DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1317 and march4l

DIOPT Version :9

Sequence 1:	NP_001163328.1	Gene:	CG1317 / 38300	FlyBaseID:	FBgn0035333	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_001038876.1	Gene:	march4l / 100000640	ZFINID:	ZDB-GENE-060825-323	Length:	421	Species:	Danio rerio

Alignment Length:	265	Identity:	57/265 - (21%)
Similarity:	97/265 - (36%)	Gaps:	72/265 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ICRVCRCEAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEYCELCSYSFSFQPIYAPDMPRV 73
            :||:| .:......|..||.|:||::..|:.||:.|:.......||||.|.:....|...:
Zfish   142 LCRIC-FQGPEQGELLSPCRCSGSVRCTHEPCLIKWISERGSWSCELCYYKYQVIAISTKN---- 201

  Fly    74 LPIKDVLVGL-------MSAVLEGARCWLHYTLVGLAWFGVVPLSAYRTYRYLFRA-----SSFD 126
             |::...:.|       ::|.:.|: .:|..::..|.|..:.|.:.::....||:.     ...|
Zfish   202 -PLQWQAISLTVIEKVQIAAAVLGS-LFLIASISWLVWSSLSPSAKWQRQDLLFQICYAMYGFMD 264

  Fly   127 MILTL--------PFDIFS----------------VENLASDAFRGCFVVTCTLLSFIGLVWLRE 167
            ::...        .|.||:                |::.......|....|.:|
Zfish   265 LVCIALIVHEGPSVFRIFNRWQAVNQQWKVLNYDKVKDNEDHQKTGATFRTLSL----------- 318

  Fly   168 QILHGGGPDWLERD----DAPLQAAAA-----------NPAPDPAAEAAPQPQDDNNNADDNEAP 217
            .:.|..|....|.:    .:.|.||||           |..| |||.|..:|||  ::...|..|
Zfish   319 PLTHRMGQSGPEGEPSTSTSSLMAAAAAAAAGTVTPTTNSVP-PAAGATTEPQD--SSEPSNGQP 380

  Fly   218 APADN 222
            :..|:
Zfish   381 SLPDH 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1317	NP_001163328.1	RINGv	9..56	CDD:128983	15/46 (33%)
CG1317	NP_001163328.1	DotA_TraY	<737..913	CDD:275142
march4l	NP_001038876.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	60..79
		RINGv	143..188	CDD:128983	15/45 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	319..385		19/68 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..421
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810