DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13807 and Ramac

DIOPT Version :9

Sequence 1:	NP_647706.1	Gene:	CG13807 / 38290	FlyBaseID:	FBgn0035323	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	NP_080273.1	Gene:	Ramac / 67148	MGIID:	1914398	Length:	119	Species:	Mus musculus

Alignment Length:	160	Identity:	48/160 - (30%)
Similarity:	59/160 - (36%)	Gaps:	62/160 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 NFLESCELEFADRFTDDDPEFMAHCSKPVPEPPIVENWMGGGGGGGGFQGGGGGGHPYHNRYNGH 81
            ||.|.    ||.|||.||.|:..:..:|...|||||.|....||                  |..
Mouse    10 NFEEM----FASRFTKDDKEYQEYLKRPPESPPIVEEWNSRAGG------------------NQR 52

  Fly    82 RRGGGDRGWQRRGGAGYHNNQDRGFRDNRRNNRYDHIDRRNRYEGGGGSGGSGGYKR-------- 138
            .||    .|.:      .|.|.|| |||||....|  :|.|::.  |.|.|:..|.:
Mouse    53 NRG----NWLQ------DNRQFRG-RDNRRGWPSD--NRSNQWH--GRSWGNNNYPQQRPEPYYQ 102

  Fly   139 ----SHDHNQRNDTPNNEPPMKVRRDYGNF 164
                .:.||||       ||      ||.:
Mouse   103 QQYTQYGHNQR-------PP------YGYY 119

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13807	NP_647706.1	RAM	21..106	CDD:291966	24/84 (29%)
Ramac	NP_080273.1	Interaction with RNMT. /evidence=ECO:0000250\|UniProtKB:Q9BTL3	1..55		21/66 (32%)
		RAM	10..87	CDD:291966	37/113 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..119		37/134 (28%)
		RNMT-activating domain. /evidence=ECO:0000250\|UniProtKB:Q9BTL3	36..42		4/5 (80%)
		RNA-binding. /evidence=ECO:0000250\|UniProtKB:Q9BTL3	56..119		25/86 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR48168
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	2.060