Protein Alignment CG13924 and CCDC181

DIOPT Version :10

• Sequence 1: NP_001189024.1
• Gene: CG13924 / 38247
• FlyBaseID: FBgn0035286
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001287898.1
• Gene: CCDC181 / 57821
• HGNCID: 28051
• Length: 509
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 98/503 - (19%)
• Similarity: 192/503 - (38%)
• Gaps: 117/503 - (23%)

  Fly    27 VNEYNIVDRIK------EANKELFALDDEASNGNGKVTKVKFALNLED------------YEPTE 73
            :||....|..|      :..|:|..|.:|....:..:  ::.|...|:            .|.|:
Human     1 MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASI--IEMACEKEENINQDLKENETVMEHTK 63

  Fly    74 QQKDLSPSPPDELLQQLTQL-------KLKPIAEEEPAAADETKVVETPPPMEEPQVDDEVEEEI 131
            :..|...|..||:..:...:       .|.||::.:...:.:...:|:...:||.: |:||...|
Human    64 RHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEE-DEEVRRYI 127

  Fly   132 CEEIVDLSEVPQQPVVQEATPIED--EDDFSGVDE-ADLDDDPPAKDSSV-PGSLQLRQGTFDQ- 191
            .|:||..::     ::|...|:.|  |......|: .|| :.||.:|::. ....:..:..|.:
Human   128 MEKIVQANK-----LLQNQEPVNDKRERKLKFKDQLVDL-EVPPLEDTTTFKNYFENERNMFGKL 186

  Fly   192 ------DDSDQKSLTNLLTESDCEE-EERTLNEARQKLRDAYKNLYKTLDPKQQETIDRLTGAET 249
                  :|..|:.:...||...||| ::||:...    ||....|....|...|..:
Human   187 SQLCISNDFGQEDVLLSLTNGSCEENKDRTILVE----RDGKFELLNLQDIASQGFL-------- 239

  Fly   250 EVPLPAPAPVVAAVEAEEEDDLSIIVASYIPDDFELNEQSIYYKKEEPDEVRDSCTTCPKATSKT 314
                    |.:....:.|.|...::..|        :..|:...|:|     ||.......|..:
Human   240 --------PPINNANSTENDPQQLLPRS--------SNSSVSGTKKE-----DSTAKIHAVTHSS 283

  Fly   315 FFTSRSFSFRRRP----KPTPTLSSASASTTSPSVRMNYKICCEHRHSIQGKLPRYTGYMSEYGL 375
              |....::..:|    |..|: |:.::..:..:.:.|::....|...:          .|.|.|
Human   284 --TGEPLAYIAQPPLNRKTCPS-SAVNSDRSKGNGKSNHRTQSAHISPV----------TSTYCL 335

  Fly   376 TAQQLQRRDQQLRRKQRFSMEQTINRNEQELKKMQDNERAFTTWLKNK------MRYPINKTRNM 434
            :.:|.:.:.|...::::...|:...:.|:|.:|.::|:..|..||:.|      || .|.:.:.:
Human   336 SPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMR-RIQRAKEI 399

  Fly   435 FDAHKRRGSVAAAGSPRQHPQAHPHL-----HQEQ-EQRGGRRRRRRD 476
            .|.:.|:        ..:.||....|     |:|| ::|.....|:::
Human   400 EDMNSRQ--------ENRDPQQAFRLWLKKKHEEQMKERQTEELRKQE 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13924	NP_001189024.1	None
CCDC181	NP_001287898.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..120		12/74 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..367		24/151 (16%)
		DUF5401	<338..>500	CDD:375164	24/111 (22%)