Protein Alignment Cdc37 and CDC37

DIOPT Version :10

• Sequence 1: NP_477006.1
• Gene: Cdc37 / 38232
• FlyBaseID: FBgn0011573
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_010452.1
• Gene: CDC37 / 851746
• SGDID: S000002575
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 513
• Identity: 109/513 - (21%)
• Similarity: 203/513 - (39%)
• Gaps: 161/513 - (31%)

  Fly     2 VDYSKWKNIEISDDED-DTHPNIDTPSLFRWRHQARVERMAEMDHEKDELKKKRQSY-------- 57
            :|||||..||:|||.| :.|||:|..|..:|:.|:..|:..:.:.:...|:.:...|
Yeast     3 IDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQVDMYSHLNKRVD 67

  Fly    58 -------QARLMDVK----------ERISKKDGDE----------------EALKKELEKIEAEG 89
                   ::.|.|:.          :::.|..|:.                |.|.|:|:|   ||
Yeast    68 RILSNLPESSLTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEMVEDLFEQLAKDLDK---EG 129

  Fly    90 KELD--------------RIESEMIKKEKKTPWNVDTISK------------PGFEKTVINK-KA 127
            |:..              :|:|..::.:||    :|.:.|            .||:.:.:|| |.
Yeast   130 KDSKSPSLIRDAILKHRAKIDSVTVEAKKK----LDELYKEKNAHISSEDIHTGFDSSFMNKQKG 190

  Fly   128 GRK-----PDENLSEEEREQRMKQFVKEN---------------EKLCQQYG--MLRKYDDSKRF 170
            |.|     |.|.||.......:.:..|.:               .|..:::|  .:.:|..|::|
Yeast   191 GAKPLEATPSEALSSAAESNILNKLAKSSVPQTFIDFKDDPMKLAKETEEFGKISINEYSKSQKF 255

  Fly   171 LQEHLHLVGEETANYLVIWSINLEMEEKHELMAHVAHQCICMQYILEL--AKQLD-VDPRA---C 229
            |.|||.::.|:..:.|::.:...::....::...|.||...|.||.|:  .|::. ::|..   .
Yeast   256 LLEHLPIISEQQKDALMMKAFEYQLHGDDKMTLQVIHQSELMAYIKEIYDMKKIPYLNPMELSNV 320

  Fly   230 VSSFFSKI--QHCHPEYRAQFDSEIEGFKGRIQKRA----QEKIQEAIAQAEEEERKERL----- 283
            ::.||.|:  ....|..:..|...::.....||||:    ||::.|:.|:..|..:.:.|
Yeast   321 INMFFEKVIFNKDKPMGKESFLRSVQEKFLHIQKRSKILQQEEMDESNAEGVETIQLKSLDDSTE 385

  Fly   284 -----------GPGGLDPADVFESL-PDELKACFESRDVELLQKTIAAMPVDVA-KLHMKRCVDS 335
                       .|..:....||::| |::::....:::::.:.|....:|::.| ||
Yeast   386 LEVNLPDFNSKDPEEMKKVKVFKTLIPEKMQEAIMTKNLDNINKVFEDIPIEEAEKL-------- 442

  Fly   336 GLWVPNAADLEG---------------DKKEEDDSD---------DVAGGEEKTDDAK 369
             |.|.|..|:.|               |:.|:|..|         |..||.:..::.|
Yeast   443 -LEVFNDIDIIGIKAILENEKDFQSLKDQYEQDHEDATMENLSLNDRDGGGDNHEEVK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc37	NP_477006.1	CDC37_N	1..121	CDD:198139	41/186 (22%)
		CDC37_M	130..266	CDD:215010	36/169 (21%)
		CDC37_C	283..372	CDD:215009	24/129 (19%)
CDC37	NP_010452.1	CDC37_N	2..183	CDD:198139	41/186 (22%)
		CDC37_M	207..368	CDD:215010	33/160 (21%)
		CDC37_C	389..490	CDD:215009	20/109 (18%)