Protein Alignment Cdc37 and Cdc37

DIOPT Version :10

• Sequence 1: NP_477006.1
• Gene: Cdc37 / 38232
• FlyBaseID: FBgn0011573
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001365725.1
• Gene: Cdc37 / 12539
• MGIID: 109531
• Length: 428
• Species: Mus musculus
• Alignment Length: 437
• Identity: 196/437 - (44%)
• Similarity: 267/437 - (61%)
• Gaps: 73/437 - (16%)

  Fly     1 MVDYSKWKNIEISDDEDDTHPNIDTPSLFRWRHQARVERMAEMDHEKDEL-------KKKRQSYQ 58
            |||||.|.:||:|||||:|||||||.||||||||||||||.:...||:||       |:|....|
Mouse     1 MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQ 65

  Fly    59 ARLMDVKERISKKDGDEEALKKELEKIEAEGKELDRIE-------SEMIKKEKKTPWNVDTISKP 116
            .:|.:::  :::.||     :.|||::.||.::|.:.|       .:|.||||..||||||:||.
Mouse    66 RKLKELE--VAESDG-----QVELERLRAEAQQLRKEERSWEQKLEDMRKKEKNMPWNVDTLSKD 123

  Fly   117 GFEK---------------------------------------------TVINKKAGRKPD--EN 134
            ||.|                                             |:.......||:  |.
Mouse   124 GFSKARGHASATLMHLATPPPPMWTGWARRPRPPNPRRTPALPQPTCPLTLSQSMVNTKPEKAEE 188

  Fly   135 LSEEEREQRMKQFVKENEKLCQQYGMLRKYDDSKRFLQEHLHLVGEETANYLVIWSINLEMEEKH 199
            .|||.|||:.|.||::.||..:.:|||.::|||:::|.:::|||.||||||||||.|:||:|||.
Mouse   189 DSEEAREQKHKTFVEKYEKQIKHFGMLHRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKC 253

  Fly   200 ELMAHVAHQCICMQYILELAKQLDVDPRACVSSFFSKIQHCHPEYRAQFDSEIEGFKGRIQKRAQ 264
            .||..||||.:.||:||||||.|.||||||...||:||:....:|...|..|:|.||.|::.||:
Mouse   254 ALMEQVAHQTMVMQFILELAKSLKVDPRACFRQFFTKIKTADHQYMEGFKYELEAFKERVRGRAK 318

  Fly   265 EKIQEAIAQAEEEERKERLGPGGLDPADVFESLPDELKACFESRDVELLQKTIAAMPVDVAKLHM 329
            .:|::|:.:.||||||:|||||||||.:|:||||:||:.||:.:||::||..|:.|....||.||
Mouse   319 LRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHM 383

  Fly   330 KRCVDSGLWVPNAADLEGDKKEEDDS---DDVAGGEEKTDDAKSESA 373
            :||:||||||||:.  .|:.||.:::   |.:.....|..:.|..||
Mouse   384 QRCIDSGLWVPNSK--SGEAKEGEEAGPGDPLLEAVPKAGNEKDVSA 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc37	NP_477006.1	CDC37_N	1..121	CDD:198139	67/178 (38%)
		CDC37_M	130..266	CDD:215010	74/137 (54%)
		CDC37_C	283..372	CDD:215009	43/91 (47%)
Cdc37	NP_001365725.1	CDC37_N	1..127	CDD:198139	68/184 (37%)
		CDC37_M	183..325	CDD:215010	79/141 (56%)
		CDC37_C	337..427	CDD:215009	13/40 (33%)