Protein Alignment PolD2 and pold-2

DIOPT Version :10

• Sequence 1: NP_647659.1
• Gene: PolD2 / 38228
• FlyBaseID: FBgn0027903
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_502177.1
• Gene: pold-2 / 178077
• WormBaseID: WBGene00008722
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 129/446 - (28%)
• Similarity: 210/446 - (47%)
• Gaps: 37/446 - (8%)

  Fly     9 YENLSSIFRLKGHD----YQKQFFHLYAHRLAEMTRLLTPLAQKKWG-NKEPIKKLCELRGEQDV 68
            |:|:|..:.|...|    :.:|:|.:|..||.|:...:...|:::.| .|....:|.:  .:||.
 Worm    11 YKNVSDRYILTEKDKKGAFTRQYFEVYEARLKELKPRILENAEREIGKGKFTHSQLSD--AKQDE 73

  Fly    69 HCILIGTIFKHQAHKPSILRDISEENQLAPQPPRQNYSDP---------EDKIVLEDELQRVRLQ 124
            ...::|.|.|..|.:||||:.:..|:::|.....::..:.         ||:|.||.:.|.|||:
 Worm    74 EIFVVGVIVKRIAARPSILKSLLNEDKVAYDDYEEDAEEDEVKRYAGSIEDRIELESDKQTVRLE 138

  Fly   125 GKLNGQLLATGVVCAALGGTDSDGFFNVEDILFYESGPQKPLAPIKRSRLLVLASGLD---QLQA 186
            |.::....|||.....||....:|.|:|..:::......|.:|.   ...:...||||   .|:.
 Worm   139 GNISMDECATGCCVGVLGKLGKEGVFHVNRLVWPSVKVPKKVAV---DGTIAFVSGLDLTGDLED 200

  Fly   187 HKF-VEALNLFQYWLAGSLGNNKEAGSMVRLIVAGNSVRASA-----MAHVPTLQVARTQANAND 245
            .:. :..|.....|:...:||..:...:.||:|.|..|...:     .:.|.||.::|  |..:.
 Worm   201 DRLTISGLEFMADWMNVQVGNENQCPPIDRLVVIGPLVETKSNGCDVQSVVRTLTLSR--AEKHS 263

  Fly   246 TVQAVSQLDQWFASWARSLP----VDIMPGPYDPANFMLPQQPFHKCMFPQAAQL-ATFQAVTNP 305
            :..::..:|:...|.|.. |    ||:.||..||.:.|.|..|.|:...|:.... .....||||
 Worm   264 STASLITVDKIINSIAEK-PLVNTVDVTPGVGDPCSSMWPLPPIHRVCLPRCGMSDKKVNLVTNP 327

  Fly   306 YSCRLDEALVVGTSGQNVSDLLRSTSLDSALEALRCTLTWGHVAPTAPDTLACYPYIESDPFILR 370
            |...::...|:..||:|||:|||::...:..:|:...:.|.||||..||||..:|..|.||.|:.
 Worm   328 YEFEVNGLRVMTMSGENVSELLRTSLKWTGADAIENIIKWQHVAPNCPDTLDAFPVAERDPLIMD 392

  Fly   371 ECPHVYYAGNCESFATELHEGSEGKRTRLVCVPSFSKTQSVAVVDLDTLDCRMVNF 426
            ..|||...|| :..|...|...:|....:||:|.||||:....::|..|..:..||
 Worm   393 ITPHVIICGN-QPHAEFRHIPIDGSNCLVVCLPKFSKTRVACFLNLSDLSLKWQNF 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PolD2	NP_647659.1	DNA_pol_D_N	26..155	CDD:436215	40/138 (29%)
		MPP_PolD2_C	175..426	CDD:277333	80/264 (30%)
pold-2	NP_502177.1	DNA_pol_D_N	32..167	CDD:436215	39/136 (29%)
		MPP_PolD2_C	185..447	CDD:277333	80/265 (30%)