Protein Alignment drpr and Scarf1

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: NP_001004157.2
• Gene: Scarf1 / 380713
• MGIID: 2449455
• Length: 820
• Species: Mus musculus
• Alignment Length: 635
• Identity: 185/635 - (29%)
• Similarity: 246/635 - (38%)
• Gaps: 183/635 - (28%)

  Fly   264 GSYG----PGCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMTCDCANDAM 324
            |:.|    |..|..|   ||:.    ..:.:|.||:|.:.  .||.:..    |.....|..:.:
Mouse    20 GTQGSTLDPAGQHVC---KGSS----PSELQCCPGWRQKD--QECTIPI----CEGPDACRKEEV 71

  Fly   325 CDRANGTCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSAQC 389
            |.:. |.|.|.||:.||:|:.| |....:|.||..||.|  .....|.|.||:|||...:
Mouse    72 CVKP-GLCRCKPGFFGAQCSSR-CPGQYWGHDCRETCPC--HPRGQCEPATGDCQCQPNY----- 127

  Fly   390 TRPCTFLRYGPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCDCQNG 454
                    :|..||..|.|....:|.|..|.|.|.|||..|||...|:             |...
Mouse   128 --------WGRLCEFPCTCGPHGQCDPKTGLCHCDPGWWSPTCRRPCQ-------------CNPA 171

  Fly   455 AKCEPETGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTGERCE 519
            ::|:..||.|:|..||             :|:.|:..|:|| .:.|...:|.|.|..||
Mouse   172 SRCDQATGTCVCPPGW-------------WGRRCSFSCNCH-TSPCMQDSGRCVCLPGW------ 216

  Fly   520 RKCDTGKFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVC-RCL 583
                   :|.:|::||||....   |..|:|.|.|...:.|:.||..|..|:||..|.:.| .|.
Mouse   217 -------WGPECSRKCQCVRGQ---CSVTSGHCSCPPGFHGIRCELPCNPGHYGAQCKESCGHCE 271

  Fly   584 NNSSCDPDSGNC-ICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYI 647
            .|::|.|.:||| .|..||.|..|.:|||.|.:|..|..:||.                ||.|
Mouse   272 LNATCSPVTGNCESCKPGWNGTQCKQPCPAGTFGERCTGQCPR----------------CRLG-- 318

  Fly   648 GLTCEHPCPAGLYGPGCKLKCNCEHGGECNHVTGQCQ-CLPGWTGSNCNESCPTDTYGQGCAQRC 711
                 .||.|                     .||.|| |.|||.|..|...||..|:|:||:..|
Mouse   319 -----EPCQA---------------------ETGHCQHCDPGWLGHRCENPCPLGTFGKGCSSTC 357

  Fly   712 RCVHHKVCRKADGMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHGCVCRSGYT 776
            .......|....|.|:|..|:.||.|:..||.||:|.:|...|.||..  .||...| .|:.|..
Mouse   358 PACAQGTCDAVTGECVCSAGYWGTSCNSSCPAGFHGNNCSMPCQCPEG--LCHPVSG-TCQLGRH 419

  Fly   777 GDNCDELIASQRIADQSENSSRASVALTLVLMTLFACIIF----------------AVFIYYRRR 825
            |.|.  ||..            ..|.|.|:||.:..|...                |.|...:::
Mouse   420 GKNA--LIVG------------ILVPLLLLLMGIVCCAYCCSGTRLDPKDRPERNGAAFFRMKQQ 470

  Fly   826 V----------------SNLK---TEIAHVHYTHDTNPPSWPPNHNFDNP 856
            |                ||.|   ..::|    ||   |..|.||:|..|
Mouse   471 VWGALTNLGSALPCGSLSNYKLPWVTVSH----HD---PEVPFNHSFIEP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204
		EGF_CA	274..319	CDD:473889	10/44 (23%)
		gliding_CglD	<451..579	CDD:468178	38/127 (30%)
		DSL	567..609	CDD:473190	18/43 (42%)
Scarf1	NP_001004157.2	PHA03247	<541..781	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	549..685
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	715..820