Protein Alignment drpr and Y64G10A.7

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: NP_001255802.1
• Gene: Y64G10A.7 / 178377
• WormBaseID: WBGene00013416
• Length: 1714
• Species: Caenorhabditis elegans
• Alignment Length: 887
• Identity: 306/887 - (34%)
• Similarity: 402/887 - (45%)
• Gaps: 199/887 - (22%)

  Fly    87 CCDGYIASA-----------GECVP--------------HCSEPCQH---GR-CISP-------- 114
            |.||:..|.           |.|.|              .|.:||.|   |: |..|
 Worm   727 CPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENS 791

  Fly   115 -------EKCKCDHGYGGPACDINCPPGWYGRNCSMQCDCLNNAVCEPFSGDC--ECAKGYTGAR 170
                   .||:|..||.|..|...|.||.:|..|:|:|.|.....|:|.:|||  :|..||.|..
 Worm   792 EGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNL 856

  Fly   171 CADICPEGFFGANCSEKCRCENGGK------CHHVSGECQCAPGFTGPLCDMRCPDGKHGAQCQQ 229
            |...||.|:||.:|.:||.|.:...      ||||:|.|.|.||.||||||..|....:|..|..
 Worm   857 CDQPCPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGTCTCLPGKTGPLCDQSCAPNTYGPNCAH 921

  Fly   230 DCPCQNDGKCQPETGACMCNPGWTGDVCANKCPVGSYGPGCQESCECYKGAPCHHITGQCECPPG 294
            .|.|.|..||....|:|.|.||:.|..|:..||.|.:|..|.:.|:|..||.|....|.|||.||
 Worm   922 TCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSCECAPG 986

  Fly   295 YRGERCFDECQLNTYGFNCSMTCDCA--------------------------------------- 320
            :.|::|...|...|:|.:||..||||
 Worm   987 WSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGI 1051

  Fly   321 ----NDAMCDRANGTCICNPGWTGAKCAERICEANKYGLDCNRTCECDMEH-TDL-------CHP 373
                |.|.||...|:|.|.|||.|.|| :|.|...::|..||..|:|...: |.:       |..
 Worm  1052 CSCQNGATCDSVTGSCECRPGWRGKKC-DRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDH 1115

  Fly   374 ETGNCQCSIGWSSAQCTRPCTFLRYGPNCELTCNCKNGAKCSPV--------------------- 417
            .||.|:|..||:...|...|...|:|..|..:|.|.|||.|..|
 Worm  1116 VTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPE 1180

  Fly   418 ----------------------NGTCLCAPGWRGPTCEESCEPGTFGQDCALRCDCQNGAKCEPE 460
                                  ||.|.|..||.||:||..|..|.||::||.||:|:|||.|:.:
 Worm  1181 GLWGSNCMKHCLCMHGGECNKENGDCECIDGWTGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRK 1245

  Fly   461 TGQCLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTGERCERKCDTG 525
            ||:|.|..||....|::.|...|:|..|.:.|:|.|.|.|:|.:|.|:|..||.|::|.|.|..|
 Worm  1246 TGRCECLPGWSGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCNRPCLKG 1310

  Fly   526 KFGHDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVCRCLNNSSCDP 590
            .||..|:|.|:|  .||.:||..:|||.|.:.:.|..|...|..|.:||:|.:.|.|..||.||.
 Worm  1311 YFGRHCSQSCRC--ANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDA 1373

  Fly   591 DSGNCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYIGLTCEHPC 655
            .||.|.|..|.:|:||...|..|.:|.:|.:.|.  ......||..||..:|..||||..||..|
 Worm  1374 ISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCS--CENGGVCDSSTGSCVCPPGYIGTKCEIAC 1436

  Fly   656 PAGLYGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVH-HKVC 719
            .:..:||.|:..||||:||.|:.:||||:||||:||..||:.||...:|.||.::|||.: |  |
 Worm  1437 QSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTCNQVCPEGRFGAGCKEKCRCANGH--C 1499

  Fly   720 RKADGMCICETGWSG-------------------------TRCDEV------------------C 741
            ..:.|.|.|..|::|                         .|||.|                  |
 Worm  1500 NASSGECKCNLGFTGPSCEQSCPSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSC 1564

  Fly   742 PEGFYGEHCMNTCACPSANFQCHAAHG-CVCRSGYTGDNCDE 782
            |.||||.:|..:|:|.: ...|..|.| |:|.:|:.||.|::
 Worm  1565 PNGFYGWYCSQSCSCQN-GAHCDGADGRCLCPAGFQGDKCEQ 1605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204	3/4 (75%)
		EGF_CA	274..319	CDD:473889	19/44 (43%)
		gliding_CglD	<451..579	CDD:468178	53/127 (42%)
		DSL	567..609	CDD:473190	19/41 (46%)
Y64G10A.7	NP_001255802.1	EMI	34..104	CDD:462204
		FXa_inhibition	159..194	CDD:464251
		FXa_inhibition	200..235	CDD:464251
		FXa_inhibition	241..278	CDD:464251
		vWFA	<319..358	CDD:469594
		FXa_inhibition	366..402	CDD:464251
		FXa_inhibition	468..503	CDD:464251
		FXa_inhibition	509..544	CDD:464251
		FXa_inhibition	550..585	CDD:464251