Protein Alignment drpr and megf11

DIOPT Version :9

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_002938407.3
• Gene: megf11 / 100490321
• XenbaseID: XB-GENE-6045392
• Length: 1053
• Species: Xenopus tropicalis
• Alignment Length: 1065
• Identity: 380/1065 - (35%)
• Similarity: 519/1065 - (48%)
• Gaps: 133/1065 - (12%)

  Fly    13 LVLAQADLKDLDGPNICKRRELYNVDVVYTELQSFQERGSTWCVTFPP--RCSTYRIKHRVVNK- 74
            |||..|.|.:.:.||:|...|.|.|.|..:....|.:...|.|.....  :|:.:||.::...:
 Frog    18 LVLGTAVLLNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAYRR 82

  Fly    75 -TKTIAKNRIVRDCCDGYIASAGECVPHCSEPCQHGRCISPEKCKCDHGYGGPACDINCPPGWYG 138
             .:|:.:.|  ..||.||..|...|:|.|:|.|.||||:||:.|.|:.|:||..|...|....:|
 Frog    83 GLRTMYRRR--SQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGADCSSGCDSEHWG 145

  Fly   139 RNCSMQCDCLNNAVCEPFSGDCECAKGYTGARCADICPEGFFGANCSEKCRCENGGKCHHVSGEC 203
            .:||.:|.|.|.|:|.|.:|.|.|:.||.|.||.|.|..|.:|..|..:|:|:||..|.|.:|||
 Frog   146 PHCSNRCQCQNEALCNPITGACVCSDGYRGWRCEDWCDPGTYGKACQLRCQCQNGATCDHRTGEC 210

  Fly   204 QCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGACMCNPGWTGDVCANKCPVGSYGP 268
            .||||:||..|:..||.|.|||.|:..|||||.|.|...||.|.|..||||.|||..||.|.:|.
 Frog   211 HCAPGYTGAFCEELCPPGSHGALCELRCPCQNGGVCHHVTGDCSCPAGWTGTVCAQPCPSGRFGV 275

  Fly   269 GCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMTCDCANDAMCDRANGTCI 333
            .|.:.|:|:.|..|..::|:|:|..||.||||.:||.:.||||.|:..|||.|.|.|...||.|:
 Frog   276 NCSQECQCHNGGQCDPLSGRCQCAAGYTGERCQEECPVGTYGFQCAERCDCQNGAKCYHINGACL 340

  Fly   334 CNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSAQCTRPCTFLRY 398
            |.||:.|..|.||:|....|||.||:.|.|::.:|..|||.:|.|.|..|||...|..||....|
 Frog   341 CEPGFKGILCEERVCPEGLYGLKCNKNCPCNLTNTRGCHPLSGECTCRAGWSGLYCEEPCRPGFY 405

  Fly   399 GPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCDCQNGAKCEPETGQ 463
            |..|:..|:|.|||.|..:.|.|:||||:.|..|...|..||||.||...|:|||.|.|.|..|.
 Frog   406 GEGCQQLCSCHNGADCDSMTGRCICAPGYTGQDCSAPCATGTFGADCLSVCNCQNDAACSPVDGL 470

  Fly   464 CLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTGERCERKCDTGKFG 528
            |:|..||:.:.|..||....:|.:|.:.|.|.|:|:|:|.:||||||.||.||.|::.|..|.:|
 Frog   471 CVCREGWQGLDCSIPCSSGTWGLNCNQSCLCLNDASCSPMDGSCTCAPGWIGELCDQPCLDGAYG 535

  Fly   529 HDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVCRCLNNSSCDPDSG 593
            .||.:.|.|  :::..|:..:|.|.|...|.|:||:..|..||:|.||...|.|.|..||.|:.|
 Frog   536 MDCLEHCDC--SHADGCNPVSGHCHCLAGWTGIHCDNLCNQGYWGPNCSMTCHCENGGSCSPEDG 598

  Fly   594 NCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYIGLTCEHPCPAG 658
            :|.|:.|:.||.|...|..||||.:|.:.||:.:|.:..|.|:||...|..|:.|..|...||:|
 Frog   599 SCECAPGYRGALCQRICAAGFYGHQCSQTCPQCVHFSGPCHHVTGHCDCLPGFFGPLCNQVCPSG 663

  Fly   659 LYGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVHHKVCRKAD 723
            .:|.||...|:|.:...||.|.|.|||.|||.|.:|::.||...:|..|:..|.|.:...|...|
 Frog   664 RFGKGCAEICSCSNNATCNPVDGSCQCYPGWIGIDCSDECPFGLWGPDCSHTCNCHNEAECSAYD 728

  Fly   724 GMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHGCVCRSGYTGDNC-------- 780
            |.|.|..||:|..|.:.||..|||:.|.|.|.|.:.....|....|.||:|:||::|
 Frog   729 GECKCTPGWTGLYCTQRCPSAFYGKDCANVCQCHNGADCDHITGQCTCRTGFTGNHCEQKCPPGT 793

  Fly   781 ------------------------------------------DELIASQRI--ADQSENSSRAS- 800
                                                      :||....:|  |..||..|..:
 Frog   794 FGYGCRQLCECLNNATCDHVTGTCYCNPGFKGIRCDQAALMMEELNPYTKISPAHGSERHSAGAI 858

  Fly   801 ---VALTLVLMTLFACIIFAVFIYYRRRVSNLKTEIAHVHYTHDTNPPSWPPNHNFDNPVYGMQA 862
               :.|.|::|||     ..:|:.||:|..:...::.:|.||         |.....:..|.:..
 Frog   859 IGVIVLLLIIMTL-----LGLFLVYRQRQKDKDHDMPNVAYT---------PAMRMTSTDYALSG 909

  Fly   863 ETRLLPNNMRSKMNNFDQRSTMSTDYGDDCNASGRVGSYSINYNHDLLTKNLNADRTNPIVYNES 927
            ..     .|..:.|.:    .|...:.|....||...|          |.:|::
 Frog   910 AC-----GMERRQNTY----IMENGFKDCMKESGCSSS----------TCSLSS----------- 944

  Fly   928 LKEEHVYDEIKHKEGYKDPVKIYSKILFPEDEYDHLDYSRPSTSQKPHYHRMNDAMLNINQDEEK 992
              .|:.|..|      |||         |...|.|.:.|....:...|    .||..:    :..
 Frog   945 --SENPYATI------KDP---------PVQPYKHSESSYVEMTSPVH----TDAPFS----DMP 984

  Fly   993 PSNVKNMTVLLNKPLPPTEPEPQHE 1017
            ||:..|..|...:|......|.||:
 Frog   985 PSSKANTNVYDVEPTLSLLQEAQHQ 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	27..92	CDD:284877	17/68 (25%)
		EGF_CA	274..319	CDD:304395	21/44 (48%)
		DSL	<479..518	CDD:302925	19/38 (50%)
		DSL	<567..606	CDD:302925	18/38 (47%)
megf11	XP_002938407.3	EMI	32..99	CDD:400092	17/68 (25%)
		exchanger_TraA	<94..>311	CDD:411343	104/216 (48%)
		EGF_CA	759..804	CDD:419698	10/44 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5687
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H13031
Inparanoid	1	1.050	802	1.000	Inparanoid score	I491
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D34806at33208
OrthoFinder	1	1.000	-	-		FOG0001631
OrthoInspector	1	1.000	-	-		otm48077
Panther	1	1.100	-	-	O	PTHR24035
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1195
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160