Protein Alignment drpr and megf11

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_002938407.3
• Gene: megf11 / 100490321
• XenbaseID: XB-GENE-6045392
• Length: 1053
• Species: Xenopus tropicalis
• Alignment Length: 1065
• Identity: 380/1065 - (35%)
• Similarity: 519/1065 - (48%)
• Gaps: 133/1065 - (12%)

  Fly    13 LVLAQADLKDLDGPNICKRRELYNVDVVYTELQSFQERGSTWCVTFPP--RCSTYRIKHRVVNK- 74
            |||..|.|.:.:.||:|...|.|.|.|..:....|.:...|.|.....  :|:.:||.::...:
 Frog    18 LVLGTAVLLNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAYRR 82

  Fly    75 -TKTIAKNRIVRDCCDGYIASAGECVPHCSEPCQHGRCISPEKCKCDHGYGGPACDINCPPGWYG 138
             .:|:.:.|  ..||.||..|...|:|.|:|.|.||||:||:.|.|:.|:||..|...|....:|
 Frog    83 GLRTMYRRR--SQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGADCSSGCDSEHWG 145

  Fly   139 RNCSMQCDCLNNAVCEPFSGDCECAKGYTGARCADICPEGFFGANCSEKCRCENGGKCHHVSGEC 203
            .:||.:|.|.|.|:|.|.:|.|.|:.||.|.||.|.|..|.:|..|..:|:|:||..|.|.:|||
 Frog   146 PHCSNRCQCQNEALCNPITGACVCSDGYRGWRCEDWCDPGTYGKACQLRCQCQNGATCDHRTGEC 210

  Fly   204 QCAPGFTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGACMCNPGWTGDVCANKCPVGSYGP 268
            .||||:||..|:..||.|.|||.|:..|||||.|.|...||.|.|..||||.|||..||.|.:|.
 Frog   211 HCAPGYTGAFCEELCPPGSHGALCELRCPCQNGGVCHHVTGDCSCPAGWTGTVCAQPCPSGRFGV 275

  Fly   269 GCQESCECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMTCDCANDAMCDRANGTCI 333
            .|.:.|:|:.|..|..::|:|:|..||.||||.:||.:.||||.|:..|||.|.|.|...||.|:
 Frog   276 NCSQECQCHNGGQCDPLSGRCQCAAGYTGERCQEECPVGTYGFQCAERCDCQNGAKCYHINGACL 340

  Fly   334 CNPGWTGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSAQCTRPCTFLRY 398
            |.||:.|..|.||:|....|||.||:.|.|::.:|..|||.:|.|.|..|||...|..||....|
 Frog   341 CEPGFKGILCEERVCPEGLYGLKCNKNCPCNLTNTRGCHPLSGECTCRAGWSGLYCEEPCRPGFY 405

  Fly   399 GPNCELTCNCKNGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCDCQNGAKCEPETGQ 463
            |..|:..|:|.|||.|..:.|.|:||||:.|..|...|..||||.||...|:|||.|.|.|..|.
 Frog   406 GEGCQQLCSCHNGADCDSMTGRCICAPGYTGQDCSAPCATGTFGADCLSVCNCQNDAACSPVDGL 470

  Fly   464 CLCTAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTGERCERKCDTGKFG 528
            |:|..||:.:.|..||....:|.:|.:.|.|.|:|:|:|.:||||||.||.||.|::.|..|.:|
 Frog   471 CVCREGWQGLDCSIPCSSGTWGLNCNQSCLCLNDASCSPMDGSCTCAPGWIGELCDQPCLDGAYG 535

  Fly   529 HDCAQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVCRCLNNSSCDPDSG 593
            .||.:.|.|  :::..|:..:|.|.|...|.|:||:..|..||:|.||...|.|.|..||.|:.|
 Frog   536 MDCLEHCDC--SHADGCNPVSGHCHCLAGWTGIHCDNLCNQGYWGPNCSMTCHCENGGSCSPEDG 598

  Fly   594 NCICSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYIGLTCEHPCPAG 658
            :|.|:.|:.||.|...|..||||.:|.:.||:.:|.:..|.|:||...|..|:.|..|...||:|
 Frog   599 SCECAPGYRGALCQRICAAGFYGHQCSQTCPQCVHFSGPCHHVTGHCDCLPGFFGPLCNQVCPSG 663

  Fly   659 LYGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVHHKVCRKAD 723
            .:|.||...|:|.:...||.|.|.|||.|||.|.:|::.||...:|..|:..|.|.:...|...|
 Frog   664 RFGKGCAEICSCSNNATCNPVDGSCQCYPGWIGIDCSDECPFGLWGPDCSHTCNCHNEAECSAYD 728

  Fly   724 GMCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHGCVCRSGYTGDNC-------- 780
            |.|.|..||:|..|.:.||..|||:.|.|.|.|.:.....|....|.||:|:||::|
 Frog   729 GECKCTPGWTGLYCTQRCPSAFYGKDCANVCQCHNGADCDHITGQCTCRTGFTGNHCEQKCPPGT 793

  Fly   781 ------------------------------------------DELIASQRI--ADQSENSSRAS- 800
                                                      :||....:|  |..||..|..:
 Frog   794 FGYGCRQLCECLNNATCDHVTGTCYCNPGFKGIRCDQAALMMEELNPYTKISPAHGSERHSAGAI 858

  Fly   801 ---VALTLVLMTLFACIIFAVFIYYRRRVSNLKTEIAHVHYTHDTNPPSWPPNHNFDNPVYGMQA 862
               :.|.|::|||     ..:|:.||:|..:...::.:|.||         |.....:..|.:..
 Frog   859 IGVIVLLLIIMTL-----LGLFLVYRQRQKDKDHDMPNVAYT---------PAMRMTSTDYALSG 909

  Fly   863 ETRLLPNNMRSKMNNFDQRSTMSTDYGDDCNASGRVGSYSINYNHDLLTKNLNADRTNPIVYNES 927
            ..     .|..:.|.:    .|...:.|....||...|          |.:|::
 Frog   910 AC-----GMERRQNTY----IMENGFKDCMKESGCSSS----------TCSLSS----------- 944

  Fly   928 LKEEHVYDEIKHKEGYKDPVKIYSKILFPEDEYDHLDYSRPSTSQKPHYHRMNDAMLNINQDEEK 992
              .|:.|..|      |||         |...|.|.:.|....:...|    .||..:    :..
 Frog   945 --SENPYATI------KDP---------PVQPYKHSESSYVEMTSPVH----TDAPFS----DMP 984

  Fly   993 PSNVKNMTVLLNKPLPPTEPEPQHE 1017
            ||:..|..|...:|......|.||:
 Frog   985 PSSKANTNVYDVEPTLSLLQEAQHQ 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204	18/69 (26%)
		EGF_CA	274..319	CDD:473889	21/44 (48%)
		gliding_CglD	<451..579	CDD:468178	54/127 (43%)
		DSL	567..609	CDD:473190	19/41 (46%)
megf11	XP_002938407.3	EMI	31..100	CDD:462204	19/70 (27%)
		EGF_CA	281..326	CDD:473889	21/44 (48%)
		EGF_CA	759..804	CDD:473889	10/44 (23%)